Vasocontriction is shit.
If you are also feeling cold and numb in your feet or hands as well with sharp pains every now and again then that would be normal vasoconstriction that is considered normal and usually safe, but if it continues after you have come down and days after then you need medical attention.
What i now do is eat a lot and drink alot of liquids and take my vitamins/fish oil/magnesium etc and dont get this shit anymore through 3 day binges. It will usually appear on day 3 for me, always, before doing the above. Eating a lot during a binge has made the biggest difference in fixing side effects for me.