Heart attack and Psychedelic

[Desiderio13]

I’m looking for experiences from people who have had a heart attack and later had to reconsider or stop psychedelic use, especially LSD microdosing, psilocybin mushrooms, or THCP.

My partner had a heart attack two weeks ago. He now has two stents and is waiting for another coronary procedure. Needless to say, we are currently taking absolutely nothing and will not resume anything without discussing it with his cardiology team.

What I’m trying to understand is whether anyone here has been through something similar, and how they approached psychedelics or cannabinoids afterwards.

Before the heart attack, his use was moderate and intentional rather than recreationally heavy. He has also lived a very health-conscious lifestyle for more than 20 years: vegan diet, regular weight training, generally good habits, and no pattern of excessive substance use.

Because the event was so unexpected, I keep wondering whether LSD microdosing, psilocybin, THCP, or some combination of these could have contributed in any way — through vasoconstriction, changes in heart rate or blood pressure, platelet effects, coronary spasm, or something else.

I’m not looking for medical advice or encouragement to restart anything. I’m mainly interested in:

• people who had an MI or coronary disease and used psychedelics beforehand
• whether their cardiologist thought psychedelics/cannabinoids might have played any role
• whether they stopped permanently or eventually resumed anything
• how long they waited
• whether certain substances were considered more concerning than others
• any relevant medical literature or case reports you came across

I’d be very grateful for personal experiences, especially from people with stents or known coronary artery disease.

Thank you very much

 

[RedRum OG]

Cannabis smoking isnt great for cardiovascular health. The research is stilll in the very early stages, but it is correlated with some poor cardiovascular outcomes. I'd avoid cannabinoids, sadly, smoking in particular.

Psilocybin and LSD are not known to cause cardiovascular issues with long term use.

MDMA would be a horrible choice, and should be avoided at all costs (some consider it a psychedelic drug)

 

[Desiderio13]

Thank you very much for your time!

 

[4DQSAR]

Well, chronic use of 5HTa (partial) agonists could potentially have off-target 5HT2b activity.

I'm pretty sure someone posted a massive table on how selective a whole raft of psychedelics are.

Of course the problem is there will always be 'zebras' - people who experience extremely rare side-effects.

After my last near-death experience I reevaluated the value of using ANYTHING unprescribed and concluded that I've pushed my luck just about as far as possible thus have none left. So I quit.

I with them a swift recovery.