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  • BDD Moderators: Keif’ Richards

Has anyone ever developed a physical aversion to certain drugs?

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PlurPsyed

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Dec 11, 2011
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My second time doing oxymorphone (opana) I railed 20 mg not realizing that was way too much for someone who rarely does opiates. I spent the next 10 hours puking and nodding off (it was perhaps the worst drug experience of my life). Each subsequent time I tried doing opana (there weren't that many) I would start throwing up the second that shit hit my nose. Not only that but if I just saw it, I would get nauseous. Has anyone ever experienced such a severe physical aversion to a drug before? Personally, I'm grateful it happened to me, its basically kept me off opiates. Just wondering if anyone has any common experiences.
 
It sounds like you just continually overdosed on Oxymorphone.

It's a damn strong drug, consider yourself lucky you're alive...
 
It sounds like you just continually overdosed on Oxymorphone.

It's a damn strong drug, consider yourself lucky you're alive...
The first few times were most likely overdoses, this account was my second encounter with the drug, my first experience was similar but I also had done 60-90 mg of oxycodone along with 20 mg of oxymorphone and attributed the negative effects to the combination. But each subsequent time, no matter how tiny the dose, I would start vomiting the second it hit my nose, before it even had time to take effect.
 
this sounds like a classic case of conditioned stimuli:conditioned response...

look up something called Pavlov's dog...

this happens all the time to humans...especially with certain foods...
 
this sounds like a classic case of conditioned stimuli:conditioned response...

look up something called Pavlov's dog...

this happens all the time to humans...especially with certain foods...
So that drug traumatized the shit out of me, basically?
 
I developed a slight, possibly somewhat lasting aversion to DXM after having a handful of unenjoyable and somewhat uncomfortable experiences.
 
never developed an aversion myself, but learnt in a psychology lesson that we can develop aversions to food quite easily, with cancer patients being advised to consume an unusual food before chemotherapy so that the nausea does not lead to an aversion to a food they usually eat. Also i know someone who after a crazy revision binge on energy drinks passed out during an exam and woke up in hospital, a few months later he threw up just from the smell of an energy drink, so it sounds likely you throwing up is, at least partly, psychological.
 
I developed a slight, possibly somewhat lasting aversion to DXM after having a handful of unenjoyable and somewhat uncomfortable experiences.

I love DXM, but after several years of excessive use simply opening the packaging to any DXM containing product makes me start gagging as does red dye. Getting that stuff down is always a struggle.



Various cough medicines, alcohol, hydrocodone, most products containing synthetic cannabanoids, and tramadol come to mind.
These have all at some point caused a physical aversion.
 
Its a conditioned response, but thats not to say you didnt overdose. When i was doing H daily for a few years, when I'd go score, on the way home i could look at the dope, smell it and instantly start heaving or puking.
 
Weed.

If I smoke it, I get an extreme case of motion sickness, where moving at all will make me throw up almost immediately, and if I stay perfectly still, the nausea will keep getting worse until I do.

The smell of weed is absolutely putrid to me and will make me gag.
 
Its a conditioned response, but thats not to say you didnt overdose. When i was doing H daily for a few years, when I'd go score, on the way home i could look at the dope, smell it and instantly start heaving or puking.

Aha, I know that feel.. I used to use stims a lot, to the point where when I would started rolling up a note I would need to do a massive shit.
 
This is kind of the opposite of an aversion, but a similar conditioned response:

when i'd be REALLY DOPE SICK, like withdrawing from lots of opana or w/e my DOC was at the time, when I'd get a wiff of some pills I''d puke. And as soon as the drugs would hit the back of my throat I'd puke too.

The relief I felt knowing that my terrible W/D were going to end was SO INTENSE that it literally made me puke, every time. Anytime I was w/d and fixed it, the rush of relief......just so intense. It was a more powerful feeling that the actual high itself, and so intense that without fail, every single time...
 
Weed.

If I smoke it, I get an extreme case of motion sickness, where moving at all will make me throw up almost immediately, and if I stay perfectly still, the nausea will keep getting worse until I do.

The smell of weed is absolutely putrid to me and will make me gag.
That's a first, lol. I always thought weed smelled yummy. I sometimes chew on it just for the taste
 
20mgs of Opana snorting it & being opiate naive basically could have easily killed you. Consider yourself very lucky & a lesson learned. Blessing in disguise in some way that will probably keep you off doing opiates for a while, if not forever.

As for your question, yes that happened to me 10 years ago with percs/oxycodone, had gotten so sick the 1st time that any time I tried it afterwards, I would get just as sick so I stopped trying/using opiates for 10 years.
 
It's quite possible to have an allergic reation to an individual drug(s).

I never made the correlation that I might be allergic to weed until someone brought it up several months ago.

I always associated allergies with anaphylaxis or hives, rather than just a general bad reaction. Now I just tell people I'm allergic, rather than trying to explain why I don't like it. Throwing up is just the worst of the bad effects, I get no good effects, just lots of bad ones.
 
I never made the correlation that I might be allergic to weed until someone brought it up several months ago.

I always associated allergies with anaphylaxis or hives, rather than just a general bad reaction. Now I just tell people I'm allergic, rather than trying to explain why I don't like it. Throwing up is just the worst of the bad effects, I get no good effects, just lots of bad ones.
Sounds like weed is not for you. Same with my nephew, he does not react well AT ALL to being stoned.
 
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