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Stimulants Harm reduction dosage

Bigfanofthemdrugs said:
^hmmmm

well i was addicted to dexedrine and adderall as well as other stimulants (eventually meth) for over 5 years, and i started at 10mg of adderall and i was tweaked off my ass. Admittedly, at the time I was only 13 years old, and I wasn't a very big guy, but even now, i see people with no amp tolerance take 20mg and they're high as a kite. Tolerance is something you want to avoid with amphetamines, which is why I said to never exceed 40mg, because after that dose, it seems that side effects get very intense, and neurotoxicity is right around the corner if you start to up your dose after 40mg. I've never exceeded 90mg, and thank god, because after that I'm just hurting my brain and body for no reason.

Remember this is an HR forum, that's HARM REDUCTION, not a "how to get as fucked up as possible".
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i'mma just say this
you mustn't have been deep in "addiction" if you never did more than 90.
it didn't take me all that long to get a tolerance to need 100-120 to get where i want.
 
It seems like doses of dexamp around 15-20mg still have some peripheral effects and slight psychological effects on me but I'm wondering what dose of dexamp is considered to cause damage of any kind to the brain and is it permanent. Thank you
 
dog it depends on you.
if 20 gets you off some, then you havent beat the shit out of ya brain too bad
i cant feel 20
i can sleep on 40
 
I was under the impression that it was difficult for a healthy person to OD on speed. I mean, people go on meth binges and stay awake for longer a week sometimes and survive. I have never heard of anyone dying purely from a methamphetamine overdose, or amphetamine overdose. Then again, I live in Michigan where methamphetamine is not too popular. But still, you always here people talking about the mythic "heroin overdose" and yet you never hear about methamphetamine overdoses. By no means am I saying that large doses are safe, they obviously put strain on your body and if you have a heart condition or some other health prroblem, you could certainly die. However, I was under the impression that it was at least possible to survive massive doses of amphetmines.

Basically my understanding was like this. With opiates, they are safe for almost everyone (except people with serious breathing problems) at low to medium dosages but once you go past a certain point, they will be lethal to almost everyone due to respiratory depression. With speed on the other hand, it is possible to die from low to moderate doses through a stroke or heart attack and yet it was also possible to survive very high doses since there isn't a direct mechanism by which speed kills you. Of course that doesnt mean you cant die from an overdose, many people would. But some people would survive masive overdoses, where with opiates, very few if any would. am I correct?

DOes anyone remember that user RyanM? I dont know whether he is alive or dead now, but he used to take massive doses of adderall and survive.
 
bronson said:
That's the tricky part about answering a question like this though, everybody is so different in their body type, and how they react to different substances. You can't really put a number on it.

Even LD50 applies to just the average, there is a good chance any given person is under or over the LD50 so I'm not sure it's really a safe guideline to go by.

Best advice I can offer is to start small, then slowly add more as you feel you must. That way you don't find yourself in a situation where you are unexpectedly in dangerous territory.
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Right of course its not a safe guideline because the LD50 means that 49% of the population would die at a lower dose than that. How much lower they dont say, but you definitely dont want to be dosing near the LD50.
 
depending on what you consider to be massive doses burn_out i might have taken "massive doses"
i've taken 180 of adderlol before at one time (i mostly used dexedrine. not too much experience with adderlol.)
last time i used dexedrine i took 120 then another 100 or 120 (idr exactly) when it came on, and i was fine.
 
damn son that crackas got me beat.
my record for amphetamine use was injecting a half gram of methamphetamine in less than 24 hours.
to be fair i smoked a little bit tho.
 
LSDMDMA&10803495 said:
i'mma just say this
you mustn't have been deep in "addiction" if you never did more than 90.
it didn't take me all that long to get a tolerance to need 100-120 to get where i want.
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Hey man, addiction is not a contest or a race, it's not really our place to judge how "deep" a persons addiction is.

HYPOTHETICALLY, what if a person had to prostitute themselves or deal or steal cars (I know I'm being extreme here) just to get their 90mg adderall? Everyone's situation is different, when it all boils down, it's not about who has the highest numbers, it's not a dick-sizing contest.
 
My LD50 is 350 mg @ the 4mg/kg ratio. I've taken 300ish/day quite a few times on top of consuming large amounts of baking soda continuously throughout the day. FWIW the vast majority of those that OD are relatively new users that haven't had a chance to develop the protective mechanisms that regular users of speed have.

If I remember correctly, the average person that suffered a fatal OD is a male in their 20's with a healthy heart.
 
I'm from Alabama and there's a pretty good amount of meth here and I have to agree with you burn out that overdosing on speed causes damage but doesn't really kill you unless it is an ungodly amount or you have high blood pressure and or heart issues. But yes there are few survivors of heroin overdoses and they are very fortunate that some higher power must see something in them or they're straight fucking lucky.

One thing I wanna understand is one time I did about 240 mg of vyvanse and I was sitting down at a friends house on the bed an when I stood up not only did everything turn black but I heard weird noises like dub step almost whah whah whah haha and I lost balance instantly and busted my ass but a few seconds later I could see and walk an I was fine so idk what was up can anyone explain
 
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RR279 said:
My LD50 is 350 mg @ the 4mg/kg ratio. I've taken 300ish/day quite a few times on top of consuming large amounts of baking soda continuously throughout the day. FWIW the vast majority of those that OD are relatively new users that haven't had a chance to develop the protective mechanisms that regular users of speed have.

If I remember correctly, the average person that suffered a fatal OD is a male in their 20's with a healthy heart.
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i've done 300mg a day a few times, and i'm fine as well.
i thought the only people who really die from speed are people who have heart conditions or something, they'll try ti for the first time/use it only a few times and just die of a stroke/heart attack..
 
Speedaddict69 said:
I'm from Alabama and there's a pretty good amount of meth here and I have to agree with you burn out that overdosing on speed causes damage but doesn't really kill you unless it is an ungodly amount or you have high blood pressure and or heart issues. But yes there are few survivors of heroin overdoses and they are very fortunate that some higher power must see something in them or they're straight fucking lucky.

One thing I wanna understand is one time I did about 240 mg of vyvanse and I was sitting down at a friends house on the bed an when I stood up not only did everything turn black but I heard weird noises like dub step almost whah whah whah haha and I lost balance instantly and busted my ass but a few seconds later I could see and walk an I was fine so idk what was up can anyone explain
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The stimulant properties of amps are acheived via secreation of catecholamines(adrenaline, etc.) from the adrenal glands. Stimulant abuse wears on your adrenals and decreases their effeciency until they recover.

The adrenals are also involved in maintaining blood pressure, so when they're weak they can cause orthostatic hypotension(a rapid decrease of blood pressure occuring when going from a sitting to standing position.) The rapid decreased cerebal perfusion causes causes the syncopal episode describing. When it occurs it's best to lay them down and alevate their legs in an attempt to accelerate blood flow to the brain.
 
RR279 said:
The stimulant properties of amps are acheived via secreation of catecholamines(adrenaline, etc.) from the adrenal glands. Stimulant abuse wears on your adrenals and decreases their effeciency until they recover.

The adrenals are also involved in maintaining blood pressure, so when they're weak they can cause orthostatic hypotension(a rapid decrease of blood pressure occuring when going from a sitting to standing position.) The rapid decreased cerebal perfusion causes causes the syncopal episode describing. When it occurs it's best to lay them down and alevate their legs in
an attempt to accelerate blood flow to the brain.
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So how could my blood pressure be low at anytime on a lot of uppers I don't understand the whole deceleration of blood flow to the brain when I stand up
 
LSDMDMA&10803644 said:
i've done 300mg a day a few times, and i'm fine as well.
i thought the only people who really die from speed are people who have heart conditions or something, they'll try ti for the first time/use it only a few times and just die of a stroke/heart attack..
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Older people are more vulnerable, but when abusing drugs most are beyond the 'I'm 25 and invincible' attitude' and generally don't push the envelop to the extent of people like you and I.
 
Speedaddict69 said:
So how could my blood pressure be low at anytime on a lot of uppers I don't understand the whole deceleration of blood flow to the brain when I stand up
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Low blood pressure in general isn't the problem, it's the body's inability to rapidly adapt to changes in posture which causes the blood to pool in the lower body instead of perfusinig the brain. To test the theory out, when you think you're vulnerable palpate your pulse while sitting and then stand up. If you have orthostatic hypotension your pulse will increase sustantially as soon as you stand in an attempt to compensate for the decreased pressure in the form of an increased heart rate.

Google orthostatic hypotension and/or syncope for more information.
 
i've had shit happen on speed where i stood up, then got lightheaded, fell down (like i mean DROPPED) and was unable to get up for a second.
 
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