Halogen element never been used in phenethylamines? At (Astatine)

[subdefy]

^ What about 2C-E?

 

[Smyth]

Well I think bromine is the best halogen for the 2,5-DiMeO drug molecule. However iodine is a very valuable asset since it is useful for imaging purposes to map this wonderful drug in-vivo.

 

[fastandbulbous]

^ What about 2C-E?

I think he's talking about halogen derivatives

 

[GFunk02]

^ Correct. E is ethyl which is a few atoms, no halogen.

2C-E is the most potent, being slightly more powerful than 2C-I.

 

[C6H6]

^ 2C-P is about twice as potent as 2C-E

 

[Smyth]

Really this is the first time I have seen this published anywhere. I would seriosuly consider this an interesting find, though maybe not quite as good as 2c-b but still interesting. A chemistry prof told me bromine is the same size as C6H6. Perhaps a slight exageration but this claim should be put to the test though I doubt it will yield anything that great.

 

[fastandbulbous]

I think it's got more to do with the charge distribution of the delocalized electrons, than purely the size of the group attached to the 4 position

 

[InfiniteBITCH]

Yes, fastandbulbous is correct. The electronic characteristics of bromine and benzene are very different.

 

[kaoskid]

putting astatine in your body is like asking for a plutonium cocktail. also there are only about 1.2 grams of natural astatine on earth (i don't believe anyone has ever isolated a visible quantity).