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Guide To Potentiating Tramadol?

riptaz

Bluelighter
Joined
Apr 30, 2011
Messages
67
Hi

Does anyone know of anything that will potinate tramadol Ive tried grape fruit juice but that did not work. I don't want to increase and seditive effect just the rushy happiness it gives. I live in the UK is there any OTC meds that cud help potinate the trams?

Any ideas or advise would be appriciated.


Thanks Guys :)
 
not really. benedryl and other anti-histamines lower the seizure threshold so they aren't safe to combine with tramadol. DXM is affects serotoni and epinephrine and should not be combined with tramadol due to risk of serotonin syndrome. aleve (naproxen sodium) could be used to aid with pain relief, but the safe and enjoyable options require prescriptions or are illegal.
 
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smoking weed?

This is the advice every stoner gives me and I blow it off. "Smoke weed, it cures everything -_-"

Real talk- Vitamin B12/6 : 100mg of caffeine : Plenty of sleep

I love tramadol to death, but I can't really think of that many things that go really well with it that are not downers.
 
use the search engine please- this has been discussed adnasuem on bluelight. http://www.bluelight.ru/vb/threads/582532-Potentiating-Tramadol-(the-technical-way)?highlight=cyp2d6

Typical codeine potentiators should work: http://en.wikipedia.org/wiki/O-Desmethyltramadol both share cyp2d6. Gaba drugs synergize nicely, but the only "otc" gaba I can think of is alcohol, which also lowers the seizure threshhold. I'm fairly certain fat doesn't increase bioavailability, so take it on an empty stomach of at least 4 hours i.e. only drink water.

It's not worth abusing, but if you insist:
Take a CYP2d6 inducer
Take another opiate
Take an antihistamine

With any luck that should do it for now. The majority of codeine potentiators should work (minus cyp3a4 inhibitors)
 
Benzos potentiate tramadol and if u really wanna potentiate tramadol n increase da happiness effect try pregabalin (lyrica)
 
There are several ways to potently potentiating tramadol and one method takes it to the extent of making it as strong as heroin. Drop 400 milligrams of tramadol in order for this to work. If you don't have a tolerance or have no experience with tramadol before try half of that amount. At the same time drop a good dose of the benzodiazepine of your choice. What I would suggust is somewhere along the lines of 2 milligrams of alprazolam or 2 milligrams of clonazepam. This will significantly decrease your chances of a seizure too. Here's the the secret ingredient to making hugely potent: after 2-3 hours of injesting the tramadol when your body starts converting it into o-desmethyltramadol (depending on your food intake and your metabolism) smoke between 0.1-0.3 (depending on the brand) of strong JWH. The brand I used with my friends was probably some variation of JWH called space and jungle berry respectively. The nod is so strong and so enlightening that you will be in dream like semi conscious state of bliss for 16 hours (only needing to redose on the herb during that period) rivaling that of the strongest opioids. I know these are strong claims but don't judge it until you try it.

The second best way to potentiating tramadol is taking a similar dose as mentioned in the first method but with half the amount of benzodiazepines and add about 900 milligrams (given that you have tolerance) of carisoprodol instead of the JWH. I couldnt add more because the carisoprodol in my country contains a large amount of paracetemol. Make sure you don't add JWH with this combination as from my decade or so of messing around with tramadol this was one combo that aggravated a seizure in me and others. The combination of tramadol+benzodiazepine+carisoprodol is so intensely relaxing that you will have no other option but to melt in your spot. This combination is obviously done with other opioids but without the benzodiazepines so I'm sure many will agree is very euphoric.

When I couldn't get a hold of JWH, carisoprodol, or benzodiazepines, being a long time lurker of bluelight (unable to post due to my old ISP monitoring the entire countries Internet through proxy), I decided to try some OTC items I started with promethazine and I have to say I was very disappointed. Mixing it with heroin, oxy, or tramadol I found that it took away from the high. However I was able to try another OTC combination described here by another user as a "pseudo-MDMA" high which Tramadol under 400 milligrams and phenobarbital at 120 but if you do intend on trying this do not add any more drugs (especially CNS depressants) and titrate your dose of phenobarbital which can be difficult due to the time it takes to reach peak plasma levels.

The final combination which is also mentioned often here is tramadol and pregabalin which was OTC until recently because of addiction issues of 10+ grams a day habits, kidney failure, and seizures upon cessation and during use. If the pregabalin can be kept at a low a dose the mix is very enjoyable. Pregabalin blocks the release of the neurotransmitter norepinephrine which makes the the tramadol much more sedating and synergizes beautifully unlike tramadol+benzodiazepine alone would. However I cannot stress enough how many times this combination has caused myoclonic jerking and seizures that sometimes could not be controlled with benzodiazepines and required potent barbiturates. This happened to such a degree that on the generic pregabalin data sheet it clearly states: "do not mix pregabalin with medications that lower the seizure threshold."

I have plenty of experience with this because here tramadol is the substitute for MMT often prescribed in huge amounts along with carisoprodol and benzodiazepines for maintenance. It can also be found on the street for dirt dirt cheap prices. I have tried the sweetest of drug combinations and I urge you not to be skeptical and try the first one. It strongly resembles the high of IV heroin on the tail end of and MDMA high. I must also note that I was doing this combination often when my tolerance to oxycodone and heroin was low as I was on 'maintenance' for 6 months and then started dramatically increasing my tramadol dosage for these combinations reaching more than a gram. Nevertheless please don't try this as it can cause seizures as I was always using high doses of GABA agonists to negate that.
 
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Hi,

I've been off tramadol now for a week and a half. Already went through withdrawals and am 100% back to normal (was on it for 2 months). Does anyone know if I can use my last 6 pills tonight and not go through withdrawals again?
 
^ I would not recomend it, while those pills alone might not be enough to throw you back into WDs, I think it's safe to say that most of us who've been there can surmise where it might lead. You're clean now, do your self a favor and stay that way if at all possible.

If you do take them bear in mind that even if your tolerance to the opioid effects hasn't dropped a lot, dose lower than you normally would, as the SNRI tolerance diminishes much more quickly, so keeping an eye on the dose in regards to seizure threshold is very important.
 
Thanks for the reply, I did end up taking 400mg, but I did take a clonazepam with it. No withdrawals came back :)
 
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