Can grapefruit juice (as a potentiator of codeine) cause nausea?
Earlier today I decided to try using grapefruit juice to potentiate codeine for the first time since I've read that something in it inhibits an enzyme allowing higher morphine conversion. I bought a big jug of Rio Red Grapefruit juice (actually a cocktail of red grapefruit, apple and grape juices) and drank about 600ml of it over half an hour, then another 300ml or so a half hour after that.
I then drank my codeine elixir, (theoretically) 400mg extracted from AC&C pills, chasing it with some more of the juice. Almost immediately I felt nauseous, and within 5 minutes I threw up the codeine and a bunch of the juice.
I then extracted 200mg more, drank it without chasing with anything, then drank another 200mg about twenty minutes later. It worked and I'm pretty high now, no real difference in intensity but I'm wondering if the juice or whatever is in it can cause nausea or vomiting when combined with codeine, because I have taken big doses of opiates like heroin and hydromorphone and rarely get nauseous (never vomiting).