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grapefruit juice and hydrocodone

Why do you say (sic) after saying im qualified as a genius?
BTW, you spelled genius wrong.
 
I took it in my psychology (advanced) class. I'll ask my teacher tomorrow as I have a meeting with them tomorrow to get all my homework for this next month.
 
well, you'd be qualified as a genius, but you don't know what (sic) means????

Okay, that sort of IQ test has no real validity. Very few tests have been shown to have a high degree of validity. Look at what the WISC-III entails, it's a test that's well founded and has a high degree of validity.
 
Recalling what i learned from many online sources, would be LEARNING, or am I mistaken as I am the moron of bluelight.
 
Just because I don't know online slang doesn't make me unintelligent does it? Show me a college entrance exam that test you for online slang?
 
You do not know what type of IQ test it is, as I don't, I'm going to ask them tomorrow what kind it was. Then again, I am the moron of bluelight.
 
Jesus-H-Christ, does everyone have it out for me or something? Can one not ask a simple question without being called a fucking idiot? Apparently not.
 
phrozen said:
Nah, they're not prodrugs. Some people mistakingly think so.
Click to expand...

From:

http://opioids.com/chronicpain/index.html

Oxycodone is actually a prodrug. The active metabolite, oxymorphone, is produced in the liver by the enzymatic activity of cytochrome P450 2D6. (This is the same enzyme responsible for activating two other prodrugs, hydrocodone and codeine). Approximately 10% of the population have genetically low levels of P450 2D6 and thus require higher than usual doses of the prodrug to obtain pain relief. Less than optimal effects may also be expected in patients taking neuroleptics, quinine, or selective serotonin reuptake inhibitors such as fluoxetine that inhibit P450 2D6 activity.



Is this site wrong?
 
gethigh said:
I seriously wrote that myself from research I did on my own, I swear, I scored a 160 on my iq test last year. I'm dead serious.
I swear to god, opiates are my specialty. Google what i wrote, it shouldn't come up nowhere but here.
Johnnyb420 hating on me again. I swear to god (that also hates me too) that i wrote that myself.
Also, I'm very clear minded now, I just got out of the shower, haven't been high in about 3 days I think.
Click to expand...


wow 160 thats pretty high considering it is thought that einsteins IQ was 160-180 range do you really think you are in the same league as einstein?


not that IQ is that important when it comes to how smart someone is but really man 160??

i have consistently scored above 145 but in no way do i put myself in the realm of the likes of einstein

get a grip gethigh who do you think you are dealing with here??



http://www.einstein-website.de/z_information/variousthings.html#iq





if you can score 160 on an IQ test then they would have tested you further with more accurate tests like thishttp://www.nswagtc.org.au/info/identification/WISC3.html


people at that level are quite rare i could be wrong but i just dont think you are at that level


go ahead prove me wrong


dont take this as a personal attack its just when you put something like this out there you have to expect people to doubt you
 
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I'm taking the fucking test well if it will let me I will, but I am currently playing runescape :P
won't let me take it online, Ill ask my school about it, but I'd rather prove u wrong with an ACT score or SAT score.
 
gethigh said:
It does as I'm getting bright flight scholarship into college from scoring 32 on act, well at least my pretest say I will do that good, I haven't taken it yet, but I'm taking it soon, I have the act packet in my drawer. Also I think it was exceptionally gifted was what I got, and it was a 167 actually.
Click to expand...



god man if you are going to tell a lie at least make it semi believable 32 on the ACT do you know that the national average is 21.2 i mean really we are supposed to believe this rubish give me a break dude

you should keep your posts to stories of your drug escapades at least those are entertaining when you try to bullshit us with these lies it is insulting

i mean i am not even close to the smartest guy around here but do you think i am that stupid?


32 on the ACT?

167 IQ?

whats next? 2400 on the SAT?



once again this really is not a personal attack just dont take me for a fool


please prove me wrong
 
wow when i prove u so fucking wrong its just more incentive for me to stay clean and ace that fucking act.
 
Two cars start off at the same point on a straight highway facing opposite directions. Each car drives for 6 miles, takes a left turn, and drives for 8 miles. How far apart are the two cars?
u know the answer? i do. use the Pythagorean theorem if you know what that is.
 
gethigh said:
Two cars start off at the same point on a straight highway facing opposite directions. Each car drives for 6 miles, takes a left turn, and drives for 8 miles. How far apart are the two cars?
u know the answer? i do. use the Pythagorean theorem if you know what that is.
Click to expand...
you think that qualifies you as genius???

thats 8th grade math dude



here is one for you smart guy

would an atom of radioactive gold be more likely to degrade by alpha emission or beta emission?? why??


high school chemistry if you know what that is
 
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Blackgold said:
Also if you want to potentiate it take a tagamet
Click to expand...

Er no. Cimetidine (Tagamet) also inhibits other cytochrome P450 enzymes, one of which (CYP2D6) is responsible for converting codeine/dihydrocodine etc to the corresponding morphine compound by removing the O-methyl group. You want something that only inhibits CYP3A4 which is responsible for converting codeine/morphine derivatives to the corresponding norcodeine/normorphine by removing the N-methyl group.

As well as grapefruit juice, another lot of potentiators are the erythromycin group of antibiotics (as I found out quite spectacularly as CYP3A4 is also responsible for ketamine to norketamine - what should have been a light dose of ket K-holed me for over an hour!). That said though, you shuldn't take antibiotics on a random basis or you end up with drug resistant bacteria in your body and some of those are opportune pathogens that can cause fatal diseases if the find their way to the 'wrong' part of the body - Staph aureus has become the dreaded superbug MRSA (methicillin resistant Stap. aureus) by such irresponsible use of antibiotics.

If you put 'CYP3A4' inhibitors into google, you'll find a big list of drugs that do just that...


Oxycodone is actually a prodrug.
Click to expand...

Actually, oxycodone has a fairly decent affinity for the mu receptor without having to be metabolized to oxymorphone, although obviously any oxymorphone produced is going to increase the opiate effect


would an atom of radioactive gold be more likely to degrade by alpha emission or beta emission?? why??
Click to expand...

Both! Alpha emission produces the element with the atomic number 2 below gold (through losing 2 protons in the alpha particle) & beta emission produces the element with the atomic number 1 above gold as the beta particle (an electron) is formed by the disintergration of a neutron into an electron & a proton, so the nucleus gains a proton.

So do I get gethigh's gold star & lollipop (I don't care about the IQ rating as I just see such things as a way of encouraging elitism)?
 
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you are correct fast as always for the record i would not question you with such a basic chemistry question your advanced chem knowledge is one of the things that led me to exploreing chemistry


but the question was which was more likely

to which the answer is beta because of the imbalance of neutrons and protrons neutrons are likely to transform into protrons which is of course the definition of beta radiation


i agree about IQ scores but if you are going to go around claiming you are genius with an IQ of 167 you kind of open yourself up to this sort of thing
 
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