jasoncrest
Bluelighter
I'm not into herbs or stuff like that to help with anxiety, depression, etc... But I read a few things I found interesting:
According to this poster, Gotu Kola is like benzos, euphoric, similar to Lyrica, helps with depression also...
There's not much info on it on Bluelight, but I found this on Pubmed:
Has anyone tried Gotu Kola?
Do you think it's worth it, or just some weak herbal crap?
Does anyone know the pharmacology of Gotu Kola?
What substances does it contain?
Concerning anxiety, is it like benzos, more like Kava, or more like Valerian?
MolokoVelocet seems to find it very enjoyable...
There's not much infos on it on Bluelight or on the net, so if anyone knows anything about Gotu Kola, his informations will be welcomed.
MolokoVelocet said:The shit alone (note: he talks about Gotu Kola) is benzo-quality anti-anxiety with really nice euphoric aspect
and has an unbelievable synergy with lyrica. Studies show it significantly ups
levels of all amines in the brain and plays with the GABA system which i dont doubt.
Id chose Lyrica + Gotu Kola over Lyrica + Benzos any day.
MolokoVelocet said:Gotu Kola alone is actually very similair to Lyrica is numorous ways.
Both are as effective as benzo's for my anxiety and both are miracle drugs
as far as im concerned regarding depression.
According to this poster, Gotu Kola is like benzos, euphoric, similar to Lyrica, helps with depression also...
There's not much info on it on Bluelight, but I found this on Pubmed:
Pubmed said:Evaluation of anxiolytic properties of Gotukola - (Centella asiatica) extracts and asiaticoside in rat behavioral models.
The ayurvedic medicinal plant Gotukola (Centella asiatica) was evaluated for its anxiolytic properties. Specifically, this study assessed the effects of: Gotukola plant materials of different genotypic origin; hexane, ethyl acetate and methanol extracts of Gotukola; and asiaticoside, a triterpenic compound isolated from Gotukola. Various paradigms were used to assess the anxiolytic activity, including the elevated plus maze (EPM), open field, social interaction, locomotor activity, punished drinking (Vogel) and novel cage tests. The EPM test revealed that Gotukola, its methanol and ethyl acetate extracts as well as the pure asiaticoside, imparted anxiolytic activity. Furthermore, the asiaticoside did not affect locomotor activity, suggesting these compounds do not have sedative effects in rodents.
Pubmed said:[Effects of total triterpenes of Centella asiatica on the corticosterone levels in serum and contents of monoamine in depression rat brain]
OBJECTIVE: To investigate the possible effect of antidepressant effect of total triterpentes of Centella asiatica. METHODS: The corticosterone levels in serum were measured by fluorescence spectroscopy. The contents of monoamine neurotransmitters and their metabolites in rats cortex, hippocamopus and thalamus were evaluated by using HPLC with electrochemical detector. RESULTS: Significant reduction of the corticosterone level in serum and increase of the contents of 5-HT, NE, DA and their metabolites 5-HIAA, MHPG in rat brain were observed. CONCLUSION: The antidepressant effect of total triterpenes of Centella asiatica may be involved in ameliorating the function of HPA axis and increasing the contents of monoamine neurotransmitters.
Has anyone tried Gotu Kola?
Do you think it's worth it, or just some weak herbal crap?
Does anyone know the pharmacology of Gotu Kola?
What substances does it contain?
Concerning anxiety, is it like benzos, more like Kava, or more like Valerian?
MolokoVelocet seems to find it very enjoyable...
There's not much infos on it on Bluelight or on the net, so if anyone knows anything about Gotu Kola, his informations will be welcomed.