It all depends on how pure the drugs are and how high your tolerance is...45mgs of crack would most likely barely register, 50mgs of meth unless it's super good is a pretty pedestrian dose....Mixing those two things is unpleasant at best anyway...
the 100mgs of heroin....Ive seen people nod for hours from less than half of that, but if it's garbage or if you have a tolerance, you might not even feel that either...
In theory, it could kill you...In reality, I'm leaning towards it being a huge dud where one thing overpowers the other and you're left frustrated, wondering how what seems like such a hardcore drug combo could have failed...
I'm assuming you have experience with all three of these drugs...Otherwise, it makes no sense to be so reckless...Take your time, you have your whole life to experiment with drugs...
Mixing opiates and stimulants is tricky business from a safety standpoint, but it's also hard to correctly balance them to achieve what you're really looking for...which I assume is the legendary "speedball" high....
I don't want to encourage you to try this, but even if you did, unless you've already determined what you're working with, it's not gonna do what you're expecting anyway.....
I remember a thread from over 3 months ago with someone wanting to try this crack/meth/heroin thing....It was ridiculous then and it's still a bad idea...Save it for when you're in your 30s and so strung out that nothing gets you high anymore....Until then, try safe amounts of one drug at a time...