Sub is pretty safe to drink on, relatively speaking. There's more chance of getting respiratory depression from mixing booze and codeine. Not that I advocate tempting fate, but I used to drink a lot more than the equivalent of two bottles of wine on top of it. Hammered the benzos too. Obviously it's best not to take the chance though.
I'm drinking Copper Dragon Golden Pippin. Beautiful. The perfect way to unwind after a rather painless and pleasant psych appointment.