Misc GBL overdose risk and dopamine rebound quiries

[Harambulus]

I'm interested in using this mainly only as a sleep aid rather than for direct recreational uses either after stimulants or just now and then when I find myself unable to fall asleep as I often have alot of trouble with the initial falling asleep but am fine once I drop off.

With regards the overdose risk...as I will be alone any time I take it in my flat I want to know the risk of overdosing on it cos I'd likely be fucked cos noone would find me til too late..So is it really a risk or not so as long as I am carefully measuring my dose- if so how easy is it to measure the dose?

Also with regards this 'dopamine rebound' effect does it cancel out the sleep benefits? I would only use it for a night after stims or now and then when I find it hard to get to sleep. I want it specifically to drop off to sleep as that is what I have so much trouble with. I have read that as soon as the gbl wears off the dopamine rebound wakes you right back up and can't get back to sleep unless you take more gbl. Is this true or is there ways to avoid such an occurrence? If there weren't that would pretty much defeat the object.

 

[grimmo]

I'm interested in using this mainly only as a sleep aid rather than for direct recreational uses either after stimulants or just now and then when I find myself unable to fall asleep as I often have alot of trouble with the initial falling asleep but am fine once I drop off.

With regards the overdose risk...as I will be alone any time I take it in my flat I want to know the risk of overdosing on it cos I'd likely be fucked cos noone would find me til too late..So is it really a risk or not so as long as I am carefully measuring my dose- if so how easy is it to measure the dose?

Also with regards this 'dopamine rebound' effect does it cancel out the sleep benefits? I would only use it for a night after stims or now and then when I find it hard to get to sleep. I want it specifically to drop off to sleep as that is what I have so much trouble with. I have read that as soon as the gbl wears off the dopamine rebound wakes you right back up and can't get back to sleep unless you take more gbl. Is this true or is there ways to avoid such an occurrence? If there weren't that would pretty much defeat the object.

You need a liquid measuring thing you can get very cheaply at chemists. Sorry I can't remember what its called. It accurately doses up to 3ml.

After about 2 or 3 hours you may find you wake up when the stimulant side of gbl manifests itself. Sometimes you can get back to sleep but other times people dose again to get a good 7 hours in total sleep.

 

[Harambulus]

Ye, I mean if you did a redose as you awoke and then got 7 total wouldn't the dopamine rebound at the correct time then so you'd awaken with a boost of dopamine when you normally would anyhow?

I normally get up to take a piss at least two or three times a night anyway so that wouldn't be much of an issue.

The only concern I had with this rebound thing is how long lasting it is...i.e. if the rebound lasted into the next night causing insomnia thereafter, then it would defeat the object, but a quick redose wouldn't be too much of an issue, although not ideal. So is it only temporary the rebound such that you should be back to normal mentally for the following eve?

Ye the measuring thing is a pippete afaik. I remember that I can buy st. johns wort or any other one of those liquids and they come with 5 ml pippete failing the chemist.

 

[QuasiStoned]

Dopamine rebound was initially suggested to be the cause of the stimulation but I think it may actually be slightly different than that, at least according to some of the most recent research done.

GHB binds primarily to two sites in the brain, it has a high affinity for aptly named GHB receptor (which I believe was discovered thanks to GHB) and has a relatively low affinity for the GABA B receptor. In small doses, GHB is primarily a stimulant because the GHB receptor, though poorly understood, appears to have stimulant type effects. As the dosage increases, GHB begins to work on the GABA B receptor and causes intoxicating and more recreational effects.

When you take a relatively large dose of GHB and it is sufficient to knock you out, you will fall into a deep sleep (sometimes more like a coma if you take too much, be careful) for the duration of time that you have high enough concentrations in your brain. As your body metabolizes the GHB, the first thing that happens is the drug stops effecting the GABA B receptor and only effects the GHB receptor. You essentially lose the sedation and and become stimulated.

I never tried pure GHB but I used 1,4 BDO a number of times. I would often use it as a sleep aid when I was in opiate withdrawal, but I found it difficult to nail the dosage and would often fall asleep sitting up in my computer chair, head down and drooling on my shirt. While it helped with the withdrawal initially after taking it, I would always feel terrible after it wore off. I would usually sleep for a couple of hours and then wake up feeling hung over but hopelessly awake.

 

[Harambulus]

Lol that doesn't sound to promising for my requirements then!

 

[QuasiStoned]

Well you can redose to go back to sleep but you might become dependent on this for sleep if you do it a lot. Also I never liked dosing twice throughout the night to get more sleep but sometimes after laying there for a while I would think "okay fuck this I want to go back to sleep, just for a few more hours."

 

[InHerOwnWrite]

the dopamine rebound is certainly nasty and can lead to physical dependence if you choose to redose to get yourself back to sleep or just to feel comfortable, but you don't have to worry about that dopamine rebound lasting so long that it would prevent you from sleeping the next night, like 20 hours later or whatever, as long as you're not a regular user.
also, i've found 1,4 BDO to be so much more horrible than GBL... it's less fun, less predictable, but carries all the same dependence risks. nuts to that.

 

[Shambles]

GBL is a shit sleep aid. Knocks you out for a coupla hours then wake up wired, redose, rinse, repeat. Sounds okay in theory but then you need to keep dosing through the day to avoid feeling bleurgh, in my experience. Then you either have insomnia again the second night or have to KO dose again... vicious circle which leads to addiction very quickly indeed. I would never rely on GBL/GHB to sleep. Once or twice if it's absolutely necessary but benzos or other options are of much more use in every way. G is a recreational drug - not a sleep aid, in my opinion.

On the plus side, it's ridiculously difficult to OD on as long as you measure your doses properly and don't redose too soon or combine with other CNS depressant, of course.

 

[Harambulus]

Hmm, is this on par with benzos in terms of stimulant comedown as I have been trying to pry a benzo prescription out of my doc but he refuses cos they are 'addictive'. I think to myself if I can handle meph/cocaine addiction wise I can handle benzos but of course can't tell him that .

I was thinking it might be good to get rid of the comedown 'frights' of meph . I recall benzos did this but like I say I found them hard to get whereas it would be pretty easy (in theory) to acquire some gbl.

If I took meph in the morning and used gbl through the afternoon to tail off the meph, so long as I curtailed use a good few hours before bed would I be able to swerve the insomnia thing? Meph never gave me troubles sleeping. Strangely I found it HELPED me to sleep in some respects. Having insomnia nearly all the time on and off to some extent, which I think is stress/depression related and my doc agreed and said I am depressed yesterday recommending I go on anti depressants but I don't think I want them, I think the contentment/confident/fulfillment feeling meph brought offered succour from my usual plight thus helping me sleep after. The doc has rec'd I go on antidepressants but they don't seem appealing or really worthwhile form their write ups. I feel great self medicating with meph (note I haven't taken it in months so that isn't the cause of my depression if that's what you're thinking, I've had the existential funk most of my life though don't harp on about it and it's getting better now with good action though I have to have a release now and then and meph was great for this) so no worries there it's just the GBL rebound deal and withdrawel I'd be concerned about. I would only be taking the gbl to curb the meph so I'm guessing the withdrawal wouldn't be an issue in these low doses? The rebound thing is of bggest concern as I already have sleep troubles to it's a sensitive issue.

 

[benzofan]

Put the dopamine in your ass FANTASTIC !!!!!!!!!!!!!!!!!!!