Flushing Out Drug Users

S.J.B.

S.J.B.

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Flushing Out Drug Users
Kai Kupferschmidt
ScienceNOW
July 27th, 2012

Tabloid journalists have long known that you can discover dirty secrets by going through people's garbage. Now, researchers have done something similar in the name of science, albeit on a grander—and smellier—scale. They have analyzed the sewage of 19 European cities to find out how much of certain illicit drugs people in those cities consume.

"The technique needs further work and validation, but this paper shows that it is a feasible approach for estimating drug use on a large scale," says Fritz Sörgel, head of the Institute for Biomedical and Pharmaceutical Research in Nuremberg, Germany, who was not involved in the work.

To put figures on illicit drug use, researchers routinely use surveys, supplemented by data from police and customs. But they have been pushing for more accurate and objective methods to estimate the amounts consumed. One possibility is to sample the sewage of a city and look for chemical traces of the drugs themselves or metabolites created when a drug passes through the human body. "The surveys tell you what people take, but not how much, not how big the market is," says Kevin Thomas, a toxicologist at the Norwegian Institute for Water Research in Oslo and one of the authors of the new paper. "Sewage tells you that."

During one week in March 2011, Thomas and colleagues collected daily samples representing 24 hours of sewage flow from 21 sewage treatment plants in 19 cities across Europe—from Antwerp to Zagreb. The samples were analyzed for traces of five different drugs by local labs according to a fixed protocol.
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Read the full story here.
 
Some of the peaks may be due to drug production rather than consumption, however, Thomas cautions. For instance, sewage from cities in the Netherlands and Antwerp in Belgium showed high levels of amphetamines, but previous surveys suggest the use of those drugs is actually two to three times lower there than in the rest of Europe. Some of the substances may get into the sewer system from illicit drug production labs which cluster in the region. And a spike in the ecstasy load in Utrecht, the Netherlands, might be due to a drug bust that coincided with the testing. "We are going with the theory that they tried to get rid of the evidence by shoving it down the toilet," says Thomas.

(...)

Sörgel, a pharmacologist, cautions there is more uncertainty in the numbers because much is still unclear about drug metabolism in the body. The authors assumed that on average, 38% of a cocaine dose is excreted. "How good that value really is still needs to be shown," Sörgel says.
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Therefore, they really don't know how much of the drugs they found were taken by people, and how much were byproducts of production or flushed down the toilet.
These confounding factors really make it hard to interpret the data.

Also, I am quite sure I remember an article reporting on this study from a year ago or so.
I will look (but if anyone else finds it first, please note the address here).
 
I think I posted one on a similar tip as this here a while ago (last 3 or so months)?
 
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