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Fluoxetine and Psilocybe Tampanensis

bighooter

bighooter

Bluelighter
Joined
Mar 31, 2008
Messages
1,660
Is it safe to combine prozac with Psilocybe Tempanensis?

I have googled it and have had mixed reports from people saying that it is fine to take but you need to take more to feel it and then some people syaing not to take it.

I was wondering if anyone had any real experience in this combination.

peace. love. unity my dear friends.
 
''SSRIs
Mechanism of Action
SSRIs (Selective Serotonin Reuptake Inhibitors) work by selectively inhibiting the reuptake of serotonin. Thus, more serotonin remains for a longer period of time in the synapses. Although the different SSRIs vary in how effective they are at inhibiting 5-HT reuptake, they all do so selectively, and thus they do NOT have a direct (significant) effect on other NTs.

Common Side Effects
Insomnia, sedation (thought not nearly as severe as with the TCAs), tremor, gastronintestinal problems, rashes, sexual dysfunction (decreased libido and difficulty orgasming), acute anxiety.

Metabolism
SSRIs inhibit, to varying degrees, the enzymes CYP1A2, CYP2C19, CYP3A4 and CYP2D6. SSRIs and their metabolites can take a long time to completely leave the body. The issue with SSRIs is that in addition to the immediate effect they have on the brain, they also alter the brain in such a way that it takes some time after going off the SSRI for the brain to return to its normal configuration. How much a person's brain has been altered (and thus how long it will take for their brain to become normal again, and thus able to feel the full effects of MDMA), depends on the dose of the SSRI the person was taking, as well as the length of time the person was taking it for. So you can see, the time the person needs to be off an SSRI in order to, say, roll effectively will vary greatly from person to person. And that's not even taking into account a person's unique brain chemistry and metabolism.


Hallucinogens (LSD/Acid, psilocybin/Shrooms, Tryptamines, 2-ct-2,DPT, DMT etc, Salvia): These drugs can be safely combined with the SSRIs. Most people report that they need to take MORE of a hallucinogen to get normal effects. Thus, if you are taking an SSRI, you will probably need more of the drug to reach threshold effects. Some people find that they need to take more LSD, but that shrooms affect them normally. So be careful to start at a normal dose and only take more if you find that you need to.
NOTE: Do not take 'ayahuasca' while on an SSRI. Do not combine SSRIs with any kind of MAOI, such as harmaline.''


Why does this say it is safe to use on SSRIs then? and this is quoted from bluelight! http://www.bluelight.ru/vb/showthread.php?t=108959
 
It's safe to use them together, but there's no guarantee of reliable effects at "normal" dosage levels.

IMO it's a waste to dose while on a SSRI.
 
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