Flovoxamine and MDMA, LSD and METH AMP

[blah_blah1991]

Hey People

Got some questions for ya, one of my mates is on fluvoxamine 50mg daily (I think I will ask dose later) been on them for about six months. Two weeks ago done MDMA for the first time, they said they felt them and looked pretty fucked up (Pink supermen) talking shit etc however from what I have read the effects are greatly reduced, I also gave said person 200MG 5-HTP as I was not aware they were on anti depressants.

Another time we did LSD same thing seemed fucked up laughing all night tripping you know how it is, had two skulls each. Now I was told last week that they were on anti depressant and I got pretty shitty at them for not telling me since it is heaps dangerous especially the MDMA + 5HTP. The acid made said person think allot about past shit and although they enjoyed the experience they have been quite down for the past week.

Now I have told the person not to do any of those drugs again, they still wanna do something though and there is no way I am going to suggest opiates so the only thing that leaves is coke and meth (Hates pot).

Does anyone have any personal experiences in regards to the combo of anti depressants specifically fovoxamine and methamphetamine?

You help would be greatly appreciated
Cheers

 

[pisspotnrock]

wish I could help you on this one man but I can't... mabey it's just your mate but sounds like a dope combination ay! haha

for HR sake, someone help blah blah...

 

[Divine Moments]

Antidepressants and Recreational Drugs FAQ may be helpful

 

[xtc123]

don't know much about the combos you speak of.. but as for him maybe wanting to still try stuff perhaps weed or some benzos would be ok for him.. dont take this as true information as I might be completly wrong here and if i am guys please correct me. don't know how benzos + anti ds go..

i also have a friend, seems to get overly fkd up on the mdma and lsd and goes lil strange days later, he checked himself into hospital after a acid trip.. never even told me.. came out bout 10 days later, they put him on zyperxia.. seems it stables his mood, anti pyscotic.. psychs lsd wont do anything for him while hes on those meds.. he smokes weed but i am a bit suss on him actually doing that too since zyperxia is for skitzos too i believe? i gave him a benzo (clonezapam) seems to of just completly leveled him out and he's normal again.

had another mate on anti-d's he never told me, we took pills, wasn't mdma, bk-mdma, he got fuck all hit off 2 of them and pretty much just went to sleep within hours.. on the floor... said he prob had a buzz for 20min form 2 pills meanwhile 3 of us were buzzing for good 3-4hrs from 2 and still up 24hrs later, hardest tihng to sleep on ive had. effects just diminish totally so either stay off em or find a easyer solution just dont abuse it.

 

[blah_blah1991]

There is one thing that worries me is info on the SIGMA receptor.

http://en.wikipedia.org/wiki/Sigma_receptor

" Activation of sigma receptors by an agonist ligand may induce hallucinogenic effects and also may be responsible for the paradoxical convulsions sometimes seen in opiate overdose. Drugs known to be sigma agonists include cocaine, morphine/diacetylmorphine, PCP, fluvoxamine, methamphetamine, dextromethorphan, and the herbal antidepressant berberine. However the exact role of sigma receptors is difficult to establish as many sigma agonists also bind to other targets such as the κ-opioid receptor and the NMDA receptor. In animal experiments, sigma antagonists such as rimcazole were able to block convulsions from cocaine overdose. Sigma antagonists are also under investigation for use as antipsychotic medications."

From what I can gather from that excerpt sigma agonists such as methamphetamine, cocaine and luvox (fluvoxamine) can cause seizures, well it doesn't state that it more states that antagonists reduce risk of seizures so my logic tells me agonists would increase the risk possibly.

On the flip side this would suggest that meth-amphetamine is still enjoyable and safe with Luvox.

http://sciencelinks.jp/j-east/article/200623/000020062306A0718136.php

I will probably just tell her half a point should be fine and have some xannies on hand if she freaks out or anything.

She is only on 50MG daily and the doctor wanted to up her dose but she didn't want to. She says it makes her feel numb which she hates but allows her to function a little better. I was thinking of getting her to talk to the doctor about 5-HTP and see what he says about discontinuing the meds cause she hates them (Not for drug use, I will be advising strongly against MDMA use even if she stops the fluvoxamine)

 

[the_ketaman]

I used to be on Fluvoxamine(Luvox) and I sometimes would get something out of taking MDMA but I never had a full on roll and often wasnt sure if it was adulterants in the pills giving me a buzz or the MDMA. So needless to say I rarely even tried taking pills when on anti-depressants but I often used psychedelics andI have always used a lot of meth(IV now but used to sniff, smoke and use orally as well). LSD seems to be the best drug for when your on anti-depressants but if you are truely depressed then in my opinion you shouldnt be taking drugs fullstop. That out of the way I will share an experience I had in Amsterdam a few years ago when I was on luvox, I went to a smart-shop and bought 2 tubs of the strongest mushrooms there were and before the night was done id eaten both tubs with minimal effect and bought another box but never ended up eating them coz there was no point. I was very disappointed because im too scared to buy shrooms here in Australia, I just dont trust that someone wont make a mistake and end up killing me just because they didnt see the poisonous one. Anyway point being I think that the effects Psilocybin Mushrooms have may be greatly reduced if the used is also on Luvox. Ive never done any studying of it so dont quote me but I certainly got minimal effect whereas with LSD I would get close to full effect.

Meth I think is an awful and destructive drug so I wont comment too much on that but meth completely created my anxiety as well as a significant portion of my depression and I had ridiculous OCD for years, I dont even know why I was taking anti-depressants because I was making my life so much worse with the meth that it was pointless even trying to manage the mental problems with A-D's. I think after opiates, meth has definitely left the biggest footprint on my soul and I have used and abused a shitload of drugs in my short 21 years(on sunday! lol) If there was one drug that id say DONT DO! it would be meth before heroin. I know im rambling, I used to hate when people did this(Preaching/Rambling) but I want to help people. Everybody drop some acid, its good for the soul.(IMO)