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Bupe Find out Suboxone Accumulated Dosage

C

CodeDevelopr

Greenlighter
Joined
Jan 15, 2012
Messages
19
I am trying to get an estimation of the accumulated suboxone that is in me after certain amount of days etc..

For example if I were taking 2 and 4mg a day for a few months now, i'll say 3mg since it's in the middle, how could I figure out how much mg is in my system when I made the jump?

I found this chart which is pretty cool but it is based on 16mg a day http://www.naabt.org/tl/16mgs-11day-37halflife.jpg

Looking at that chart it looks like the accumulated dosage kind of caps out around 44mg based on taking 16mg daily, does this mean that after a certain period, it will stop increasing in your system and stay at a certain number daily?
 
Yeah, I've seen that chart too, and what it means is that it caps after 11 days. If the chart is correct, which I took it to be, than four mg would accumulate to 10 mg, 3mg would be 7.5mg, 2mg wild be 5mg,1mg-2.5 etc etc.. However I don't know if that's correct as it seems to me that buprenorphine leaves the system so much quicker at these lower doses, but who knows.
 
The best way to determine this is to use the half-life of Suboxone, which is approximately 36 hrs (which explains why bupe leaves your systems subjectively much more quickly at lower doses).
 
Right, except it's still confusing, cause if I'm at one mg a day, according to the half life chart, I have about 2.5 mg built up in my system, yet I still start to feel withdrawals twelve hours after my morning dosage, when I would still have more than one mg in my system. Though I guess that buprenorphine also increases in effects in a linear fashion up to around two or four mg, so it would make sense to reason that, it would decrease in the same linear way. And that wild also explain why at a dose like 8mg a day, it would take up to three or four days to begin to feel withdrawals.
 
^ could it be that the withdrawal that you are feeling is the dose from a few days ago leaving you? When someone is not dependent and takes a dose of bupe, it seems to last a lot longer, and if they had been dependent on another opiate before taking the suboxone, the withdrawals don't seem to come back for 3 days. At least that is my experience with it.
 
Yea it's possible it's just the dose frame a few days ago leaving me, but I would think that that would be countered that I consistently take the same amount of suboxone and have been doing so for a month, so I would imagine that it should balance out. I think what it is, is at even the the half life stays the same, the drop from .5 mg, as minuscule as it would be in a 12 hour period, is still felt, because I'm on a low enough dosage that perhaps microgram differences can be felt. That seems to make sense, but who knows.
 
Znegative said:
Right, except it's still confusing, cause if I'm at one mg a day, according to the half life chart, I have about 2.5 mg built up in my system, yet I still start to feel withdrawals twelve hours after my morning dosage, when I would still have more than one mg in my system. Though I guess that buprenorphine also increases in effects in a linear fashion up to around two or four mg, so it would make sense to reason that, it would decrease in the same linear way. And that wild also explain why at a dose like 8mg a day, it would take up to three or four days to begin to feel withdrawals.
Click to expand...

I dose 2mg 3x a day and I feel withdrawals in 8-12 hours... yawns and runny nose type. Fuck that 36 hour half life bull
 
the reason you feel withdrawals is because of a drop in your blood plasma levels but it takes more than 12 hours for them to sufficiently drop if you've been taking bupe daily for a while..... YOU DO NOT feel REAL withdrawals 12 hours after taking bupe if your taking a consistent steady dose...(probably even 24 hours)

Most of these withdrawals are psychological....

Bupe withdrawal really starts about 3 or 4 days after you don't take it...
 
Yeah that's probably true, but not all of it is psychological, especially when you're at a real low dose. If I don't take my evening .5mg within about four hours of the time I usually take it I start to get teary eyes, and a runny nose, even some hot/cold flashes. It's pretty minor, but it's definately not just psychological. I'm sure you're right though, all that probably seems like nothing compares to what it would feel like if I skipped three days of suboxone.
 
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