True, we don't know your tolerance...that aside, assuming you already have a high tolerance it is 'safe' to drink in your coffee as people actually pour that right into their mouth. The issue I wonder about is that fent won't 'bind' with coffee and you may miss it all by drinking the coffee and then see globs of it at the bottom or stuck to the cup...either that or it may make a glob that floats on top. I'd like to know how this went for you. Oh, and btw, don't forget that dosage is supposed to be 25mcg an hour,meaning the actual patch has something like 100 MG inside of it all together, Be careful. Let us know how it went