Favorite Synthetic Cannabinoid

[Shambles]

Most if not all synthetics can be used orally (or even rectally dissolved in full-fat milk or similar) but the dose has to be somewhat more precisely controlled than with weed or hash cos some of them are deeply unpleasant if you dose even a touch to high - JWH-018 leaps to mind. They don't taste that bad to smoke - kinda earthy but not too strong - and I would always go for pure powder over smoking blends. Partly cos I have a great dislike for branded legals that refuse to name their ingredients so you really don't know which chems in which quantities you are getting, and partly cos some synthetics have extremely steep dose/response curves and I wouldn't feel at all comfortable taking a completely unknown amount of them.

 

[kingme]

another vote for 073. feels cleaner somehow (though in a bit synthetic way)...

but why no love for 081? nice body high, real "stoned" feeling... was expectig to see at least one vote...

and sadly this cat never tried 018 alone, just mixed with some brand name blend.
and 250 and 200 will be next

 

[HippieChick]

my fav is Jwh-018....I like my shit strong.

wanting to try that new Jwh-200 though

Not too bad. No instant panic like can happen with 018. Makes me sorta horny, which is unusual for me and constant for my husband

 

[solistus]

I voted JWH-018 but I've only tried that and one trial of dronabinol that left me unimpressed. My friend who's tried both -018 and -073 quite a bit prefers -018 but prefers a mix of the two to either of them on its own.

I don't find -018 all that intense or anxiety-provoking, though. Maybe that's because I mostly take it orally, and when I smoke it's usually just a tiny sprinkle with some weed. The pseudo-visuals I get from weed come out at lower doses, it seems, with -018 - not visual distortions per se, just vivid imaginary images and 'eyes playing tricks on me' from the corner of my vision. I find that on its own, it produces the general effects of being stoned, but weed gives me a unique sensation that I can only describe as 'pressure' in the head, centered between the eyes, but it's a pleasant sensation and that makes it sound more like a headache...

At any rate, some of those specific queues I use to gauge how high I am and auto-titrate don't seem to be there. It's not close enough to feel just like smoking or be *as good* as the real thing, but it's good enough that if I'm out/low on weed or for whatever other reason need to go without ganja for a bit, an oral dose of -018 will satisfy my craving for being high enough that I won't be jonesing for a smoke like I normally would. Also, if I've taken a decent oral dose of -018, a single hit of high quality bud will bring out all those 'missing pieces' of the high for at least a couple hours.

 

[Banio]

I do not recommend 081, bought 1 gram, used it on 10g of marshamallow herb, smoked 1g with friend. Was feeling a little bit stoned, but nothing impressed, and it was very short, up to 30min.

 

[Lucid Dream]

I have used jwh-018, jwh-073, jwh-081, jwh-200, jwh-210, jwh-250, jwh-121, and am-694. Each compound has its uses. I think 073, and 018 have what I consider to be the more euphoric of these. But jwh-210 would be my 3rd favorite. I do NOT recommend Am-694. Jwh-200 seems to be the worst of the bunch, but in combination with 73 I think it adds something to the table.

I have to say that most of these compounds have a high that lasts 30-45 min. As for the belief that naphthalene is released in your body upon jwh-018 being metabolized, but after a year of continuous daily use, and not one symptom of naphthalene ingestion. First of all my red blood cell count is as good as it gets. If I had been ingesting naphthalene over the last year, I would definitely have a lower than average count. I'm not trying to say try these compounds because I played a Guinea pig and nothing bad happened to me. Different drugs effect people in different ways. I'm just giving as much information I have regarding the allegations of Naphthalene poisoning. I still have no definitive proof, but I feel I have enough circumstantial evidence that I'm comfortable in my decision to use these compounds. Please do your own research and make up your own mind. I am not a doctor, nor have I played one on T.V. So don't hold on to my words as if they were written by one.

 

[~_Hiss_~]

I'm going to go for -073 because I'm prone to cannabis related anxiety. Do you think it will serve me well at 4mg? If it takes something like 10 or 15mg I might just consider a careful 018 measurement, but pretty much ruled out trying 018, first anyways.

So if one or two hits of weed gets me high and sometimes anxious, I wonder what the dose of 073 would be.

LucidDream, I'm sure that will put some people's anxiety at ease. Very informative post, but could you share doses of 018 and 073, and compare them a little? Which one is your favorite?

 

[Lucid Dream]

I really don't think there is that big of a dose curve for 018 and 073. I would say 073 is about 85% the strength of 018.

Ki values are 2.9 and 9.0 nM for Cb1 and Cb2 for Jwh-018
Ki values are 8.9 and 38 nM for Cb1 and Cb2 for Jwh-073

So according to this, 018 is 3 times more potent than 073 activation the Cb1. Jwh has 4 times the potency of 073. So using just these numbers, I would say what ever dose you take of 018, just triple it for 073. But I would not suggest this either as I smoke 30mg of 018 per smoke, but only 40mg of 073.

I think the key thing here is as with all new RC's, if you have enough insanity to try, start off small and work your way up. My suggestion is smoke the same amount of 073 as you smoke of 018, and then slowly increase from there.

 

[carbon unit]

I just tried jwh250 last night and I woke up still stoned. Is this one fairly long lasting?

So far, I prefer 073.

 

[Lucid Dream]

I have always considered 250 to be more short acting over 018. So I would not think that any feelings should be felt after 2 hours of dosing. And this is enough time to reach baseline. With every person, dosage, and length of high can sometimes change.

 

[Thorns Have Roses]