When I was in high school (nearly 20 years ago), I was at a party, completely sober, and decided to start out with a massive bong rip at a table full of guys in their 20's that I had never met before. I was pretty experienced with cannabis at that point, but right after I hit the bong I fainted, hit the floor hard, and wet my pants a little. It was extremely embarrassing, but also very, very frightening. To this day I don't know exactly what caused it, but looking back, my life was full of stress. I had been kicked out of my parents' house, I had been kicked out of my band, I had just lost my job, and had just signed a lease on an apartment and didn't know how I was going to pay the rent. In addition, my dad had divorced my mother because she was addicted to meth and was losing her mind, and had just become engaged to a woman with the exact same (very uncommon) first name as my mother. Add to that the fact that I didn't really know anyone at the party, and they were all very tough, urban guys and I was more of a poetry geek, and it sorta makes sense.
I don't know if that helps, but I saw your thread and immediately remembered this episode of my life. I hope somehow it does.
edit: I said this was in high school, but it was actually the summer after graduation.