I am not sure why people would want to have pharmacologically induced nystagmus. When it happens to me, it scares the shit out of me. I know what is happening from a neural perspective.
Nystagmus is an involuntary condition. There really are not ways to "bring it on." You look quickly to either side and your eyes have a tough time catching up with the head movement & staying on a given target straight ahead...it looks wobbly sort. This would be an example of gaze-evoked nystagmus.
Horizontal and pendular...no matter where you look or turn your head everything is shaking and appears to shimmy or move rapidly.
Personally, horizontal, pendular, and gaze-evoked nystagmus are have been most common. When neurologists or ophthalmologists are trying to figure out where the brain lesion is they use the characteristics of the nystagmus observed.
Horizontal nystagmus is a well-recognized finding in patients with a unilateral disease of the cerebral hemispheres, especially with large, posterior lesions.
Pendular nystagmus is a multidirectional nystagmus (ie, horizontal, vertical, circular, elliptical) with an equal velocity in each direction that may reflect brainstem or cerebellar dysfunction.
Gaze-evoked nystagmus is produced by the attempted maintenance of an extreme eye position. It is the most common form of nystagmus. Gaze-evoked nystagmus is due to a deficient eye position signal in the neural integrator network.
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