Oh yeah. I introduced my girlfriend to LSD, and we've tripped together about six times in the last year or two. Has it strengthened our relationship? Absolutely, every time!
The first time we tripped was when I was in college. We each took one tab, which I estimate to be about 100 ug. I felt pretty cool the whole time, about what you'd expect from that kind of dose, but she took it entirely differently. Before long we both had the giggles, and then she was laughing so hard she couldn't breathe, and unfortunately that spooked her. Instantly she went from laughing to crying, uncontrollably, for what must have been an hour or so (and you know how long an hour is when you're on LSD!). It was pretty harrowing, but eventually she got over it and was able to enjoy the rest of the trip. We took a walk, looked at the ocean yadda yadda.
This and subsequent trips have made me realize something: my girlfriend loves LSD, but she has NO IDEA what she looks like when she's on it. All that crying was horrible for me, but after the fact she said "Well, I know I was crying, but I was having a good time!"
Second time was at a rave for New Year's Eve 2010-11. I went with a small group of myself, my girlfriend, and another couple. I took two tabs, (again, probably 200 ug) and I wanted to give her one but the girl INSISTED on taking two. Meantime, the other couple were taking MDMA(Though this was before bluelight, and I never saw it tested.), which I had tried before but wasn't terribly into at the time. Anyway, we all had fun for a few hours, dancing and hugging and whatnot, and my girlfriend was having a great time so I thought "Cool, guess she's more used to tripping now." Boy was I wrong!
I didn't really realize the magnitude of the situation until the rave ended- and she kept dancing. She ran around, gave some hugs and then ran up to a security guard and kissed him on the cheek! At that point the other three of us grabbed her and rushed back to the car, trying hard not to make it look like we were kidnapping her or something (bear in mind I was still tripping!). We got her into the back seat, but I wound up having to hold onto her legs because she was kicking and screaming all over the place (like, orgasmic screaming, not frightened screaming. Luckily.) That lasted for another hour or two, until she started to come down.
It turns out she'd gone into some kind of a waking dream state and was having a ++++ experience the whole time (or something like that.) She felt like she was flying through space to another world and was so happy that the other three of us were with her, etc.
To this day she's the only person I know who's had such a powerful trip, especially from such a low dose of LSD. The last few times we've tripped I've always dosed her in half-tab increments, trying to stay between 50 and 150 ug. It still seems like whenever she goes over 100, she goes through an hour or so of dissociation and bawling at some point during the trip. 8) She doesn't seem to mind though.
I've highlighted the rougher parts of our experience, because I think they're the unique parts. Most of the time, when we're tripping, everything's awesome. We've been able to have some really productive conversations about our relationship while coming down. Not to mention the fact that she suffers from some anxiety/OCD issues, but both of us agree that, for her, taking LSD a few times has had a noticeable and positive effect on her mental health.