Ethylphenidate Vs Cocaethylene

[PotatoMan]

NOT THE RC version of the drug Ethylphenidate.

Anyway, it's nearing that time for my 5-day after exam trip to a little island off Trinidad called Tobago. It's a very fast-paced 5days characterized by lots of girls, drugs, clubbing and parties. I usually go with friends.

Anyway, my drug list will be ~2 Oz and a 1/4 of weed, 20 10mg Valium and 3 bottles of scotch. Of course everyone else will have their drugs and whatnot. My biggest fear is the ability to 'keep-up' last year was 50 0.5mg Xanax(Alprazolam), 300mg codeine(pure cough-syrup), booze and >4 Oz weed and I don't remember 75% of the 5day experience.

This year I'm trying to change that as coffee didn't help much last year. I've opened my eyes to the use of cocaine to keep-up but it's too short acting and the crash is nasty. I would like to try something new like Methylphenidate as I've read the duration is much longer and I have Valium for the comedown.

I've read that;
Cocaine + Alcohol = Cocaethelyne
Methylphenidate + Alcohol = Ethylphenidate
Ritalin = Methylphenidate IR
Concerta = Methylphenidate XR
Valium = Diazepam

I love the effects of Cocaethelyne but as stated above I hate the short-duration, comedown and the higher risk of health affects.

I am trying to decide whether it would be better to take Concerta twice daily and Valium to knock me out in the after-hours or bump 10mg lines of Ritalin according to level of intoxication.

I'm a virgin to Methylphenidate and also not certain as to what I should dose. I'm 17 and weigh approx 80kg.

I was thinking taking 30mg of Concerta as I wake up on a morning with coffee and then 30mg after lunch/in the evening around 6. (Keep in mind I need to be functional 24/7 in order to 'keep-up' as the 'turn-up' does not stop. Or should I mix the Concerta dose with 10mg Valium?

What I'm wondering here is that is Ethylphenidate 'more-forgiving' than Cocaethylene? In terms of duration of high and ease of comedown?

Any advice on how much Methyphenidate to dose will be appreciated as well.

 

[PotatoMan]

Also sorry but I forgot to add.
Would it be better to take the Concerta before the alcohol or after?
Because chances are, as I wake in the morning early I was thinking of taking 1 Concerta then begin drinking probably after midday.
I guess the question here is, would it be a significant difference in euphoria if I dose this way? Or should I at least wait till I begin drinking to then take the Concerta to achieve maximum euphoria for the longest possible duration?

I know there must be booze in the liver before coke consumption for proper metabolization of Cocaethylene so this is why I ask.

 

[neurotic]

Ethylphenidate can be formed in vivo when ethanol and methylphenidate are coingested, via hepatic transesterification.[1] Ethylphenidate formation appears to be more common when large quantities of methylphenidate and alcohol are consumed at the same time, such as in non-medical use or overdose scenarios.[2] This carboxylesterase-dependent transesterification process is also known to occur when cocaine and alcohol are consumed together, forming cocaethylene.[3] However, the transesterfication process of methylphenidate to ethylphenidate, as tested in mice liver, was dominant in the inactive (−)-enantiomer but showed a prolonged and increased maximal plasma concentration of the active (+)-enanatiomer of methylphenidate.[4] Additionally, only a few percent of the consumed methylphenidate is converted to ethylphenidate so a pharmacologically significant dose would never be produced

When methylphenidate is coingested with ethanol, a metabolite called ethylphenidate is formed via hepatic transesterification,[80][81] not unlike the hepatic formation of cocaethylene from cocaine and alcohol. The reduced potency of ethylyphenidate and its minor formation means it does not contribute to the pharmacological profile at therapeutic doses and even in overdose cases ethylphenidate concentrations remain negligible.[5][82]

Summing it up, the amount of EPH made from ingestion of MPH and alcohol simultaneously is minuscule and not enough to have any effects.

However, MPH + alcohol is fun imo, best of both worlds. Coke can be more euphoric (MPH is very jittery and physical for me) but the cocaethylene will be harsher on your heart I believe, I guess it's even cardiotoxic or something. So if you're looking for a less unhealthy option, I'd go with the MPH.

The way I like to do is start drinking, and as soon as the alcohol kicks in, start the snorting. You can start with 40mg (or may be 20-30mg if you're unexperienced) and snort more over the course of the night until you're as jittery and shaky as you want. Imo the highest dose actually enjoyable would be 60mg snorted, any more than that would be pushing it and the annoying side effects will start to come such as paranoia and shakiness and excessive jitterness and of course you're closer to a heart attack. I would definitely not go over 80mg in an hour, and that's really pushing it imo.

Ime MPH comedowns aren't that harsh, but if mixed with lots of alcohol (the MPH will make you feel more sober and able to drink way more) the beginning of a hangover together with the comedown can be a bitch, and this is the time to use your Valium and knock yourself out to sleep.

 

[PotatoMan]

So what I'm getting from your post is to take Ritalin instead of Concerta because the MPH to EPH for concerta is too minimal when it comes to booze?

I just would of preferred to suck a 54mg pill of Concerta till the coating comes off and then swallow it after the alcohol has presented it's effects because it's a much more subtle ROA.

Whereas with railing 15-20mg lines of a crushed pill multiple times according to level of intoxication and then walking back into the social view of people, rubbing my nose and sniffling like if I have the flu is just a bit too explicit lol.

On this trip we'll be going to the beach like everyday and that's where I'd be drinking the most and then wherever the 'lime' is after the beach i'd be drinking.

Can't I just get 20mg pills of Ritalin and swallow them whenever I feel too drunk?

I mean I really do love the euphoric effects from stims + alcohol but if I may have to sacrifice that in order to keep up with the pace then I don't mind. Plus multiple pills of Ritalin may cost a lot more than 10-15 Concerta pills.

 

[neurotic]

Ohh yeah, I was talking about Ritalin. Never tried or seen Concerta, we don't have those around here. The MPH to EPH from Ritalin is still negligible, that's not the reason I was saying to do Ritalin haha, I just didn't realize you were talking about Concerta.

Well, I prefer snorting the MPH (which I get in form of Ritalin) because of its higher BA, shorter come up and imo higher intensity, but that's just me.

If you don't want to snort then yeah eat it, but I wouldn't know about dosing, though I believe that oral BA is lower than intranasal BA.

 

[PotatoMan]

I went to the doc today. She told me that amps and ritalin are no longer available from where I'm from. Only concerta.

This means that 18mg twice a day along with Valium 10mg at the same time will have to be the routine. Booze, weed and coffee throughout the trip.

I believe the concerta extended release effects will be enough for me to keep up during the trip.

Besides the doc also told me today that my BP is 140/80 and I'm 17 so she said no stims for a while for me. Lol. I'm sure by June 28th I'll be in the clear.

I'm starting total detoxification from today.

 

[RDP89]

Can't comment as I absolutely hate methylphenidate. I was prescribed it from 2nd grade until 6th when I refused to take it anymore. I love amphetamines and alcohol though, but since it seems you can't obtain aderall that doesn't seem an option.

 

[neversickanymore]

IMHO skip the benzos for comedown or to mediate things.. that is one of the biggest and longest running misinformation ever.. think im bullshitting.. try useing the stims and the booze, forgetting the parachute ever existed. You come down much nicer, just as fast, and with SO MUCH LESS BS to deal with in when you wake up. loose the benzos and watch your overall experience increase immensely.

Maybe throw a benzo into the mix early morning, but thats it.

Love T&T by the way.. very nice destination.. I would wish you a great time, but that assured.

 

[T. Calderone]

If blood pressure is an issue, you should take it easy on the liquor because excessive alcohol consumption can cause blood pressure to spike.

 

[PotatoMan]

@T. Calderone
Yeah the detoxification includes;
Nicotine, Caffeine, THC, DXM, Cocaine, 80proof-liquor and stimulant psyches like LSD and MDMA.

The BP issue is only until next month this time. Once I detox til then and check my BP and it's back to normal, I'm free to consume substance according. But once my BP remains elevated even without drugs then that will cause for life-changing things to take place...

During the detox I'll be consuming low doses of Diazepam, ~40mg and no more than a 6-pack of beer on the weekend in total. This will combat the nicotine and THC cravings quite well whilst not having a major effect on my BP.

Cuz I went into the doc's office today after taking 40mg Diazepam on Saturday and 10mg on Sunday and my BP was 140/80 today. So I figure the diazepam should be fine to dose along with minimal beers during the detox.

@neversickanymore
So you're saying to parachute the Concerta in the morning and take the Valium and then forget the Valium for the night? What if I get acute insomia from the Concerta?

I figure 18mg MPH with 10mg Diazepam in the morning and then at 6pm same dose should be good?

 

[bigsl33p]

EPH is definitely more cost effective and you get the happy drunk feeling while being awake/alert

 

[black53]

EPH is definitely more cost effective and you get the happy drunk feeling while being awake/alert

+1

if you want the eph high buy it from one of the many many rc vendors out there, it's common and cheap.

 

[reecep555]

I did Ethylphenidate at a two day concert and it was quite satisfying for "keeping up". As neurotic told me and is now telling you it is a very physical jittery experience.
I had around 3 beers 1 36mg concerta orally then 3 more beers. The second day I had 3 beers 36 mg orally 1 more beer around 10mg more orally and my remaining 2 beers. Around 2 hours later I got a beer inside the concert (I think it was around 500ml) after that I had the rest of the methylphenidate I had taken out of the pill.(around 25mg)
This whole time I was jittery and had enough energy to keep up with all the dancing. The second night it kept me up till 4am.
I have also read that methylphenidate and cafiene isn't a good combination. It turns out it makes you feel shitty. If the 1 concerta isn't enough on its own I don't see the harm in taking more except developing a tolerance.

 

[PotatoMan]

The concerta pill I'll be getting is 54mg. I plan to take 10mg of valium with the pill in the morning and drink throughout the day.