Benzos Ethyl-bromazolam and Ethyl-flualprazolam experiences or thoughts?

[SuperPsych]

Seems like these are gonna be part of the wave of new benzo-like drugs on the RC scene. Have read a few, not very detailed reports. Ethyl-bromazolam I have heard is a bit euphoric but thats about it. Ethyl-flualprazolam is apparantely about twice as potent as alprazolam, and the duration a bit longer, which gives me hope as I would love a benzo that lasts less than 12 hours

 

[4DQSAR]

Extensive QSAR data IS extant. Jackson B. Hester synthesized a lot of homologues and a methyl side-chain proved to be optimal.

US3987052A - 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines - Google Patents

6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines of the formula (IV): ##SPC1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, inclusive, phenyl, benzyl and -COOR' in which R' is alkyl of 1 to 4 carbon atoms, inclusive; wherein R 1 is selected...

patents.google.com

The table in column 4 shows the relative activities.

I can only guess that 8-chloro-1-methyl-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine is more expensive to synthesize on a per-dose basis and/or someone is sat on a pile of bromonordiazepam and swapping from acetyl hydrazine to propenyl hydrazine is simply the easiest next-step.

Sadly, what's best for the end-user comes a distant second to what's best for the people making such things. It wasn't as if we didn't already know that nitrobenzodiazepines were the most potent but we also knew they were also the most toxic - hence our not touching them.

But with UK law having changed, Grisham's law compels all the people in that business to focus on cost.

 

[sleezfuck]

Seems like these are gonna be part of the wave of new benzo-like drugs on the RC scene. Have read a few, not very detailed reports. Ethyl-bromazolam I have heard is a bit euphoric but thats about it. Ethyl-flualprazolam is apparantely about twice as potent as alprazolam, and the duration a bit longer, which gives me hope as I would love a benzo that lasts less than 12 hours

What is an average dose?

 

[Themailman]

What is an average dose?

Of ethylbromazolam? Start with 2-4mg and go from there. I would say 8mg is a very high dose particularly for those without tolerance. It has a short half life though, so its fairly forgiving if you take too much.

Most pressed bars contain 4-6mg

It is not more potent than alprazolam, it is roughly equipotent but feels a bit weaker and is not as potent anxiolytic wise. Just my anecdotal opinion. Ive used hundreds of mg of ethylbromazolam

Effects wise it's probably the closest to alprazolam I've ever seen from an RC benzo, but alas it feels colder and is more prone to delusional sobriety than real alprazolam.