Supeudol
Bluelighter
Ok well I recently just switched from Paxil to Effexor XR. So I was on Effexor XR 37.5mg (starting dosage) for 5 days, and then just today I went up to Effexor-XR 75mg. Well anyways, I have heard that with SSRI's and SNRI's and different antidepressants that often it can make you feel much more anxious at first.
Well, this past week I have been more anxious than usual and I am pretty sure it is due to the Effexor. Now I have been on Effexor-XR in the past, but I didn't have the anxiety side effects because I was taking medium to large dosages of benzo's and I was also on methadone at the time, so I have no idea whether it did help my bad depression and my general anxiety/panic disorder or what because basically the effexor was being masked my high dosage of methadone + benzo's. I don't even know why I went off of it. But anyway, that was a few years back.
Now I have been clean from benzo's for about 7 months now, except for a few nights I had some Valium a couple weeks ago, but it was very little and only for a few days, or even a day or two. So as of now, I am have been taking Oxycodone daily, I kind of relapsed on that, and my tolerance seems to be going right back to where it used to be (600mg/day), but nowhere near that dosage yet. My daily Oxycodone dosage is usually about 160mg - 220mg daily. But I take Diphenhydramine on a daily basis, right before I dose my Oxycodone, in order to potentiate the effects.
So basically I am wondering if I should be taking the diphenhydramine or not since I now am on 75mg of Effexor-XR. I cannot remember if Diphenhydramine and SSRI's, or SNRI's whatever is a harmful combination? And also if other people noticed increased anxiety from starting Effexor-XR? I have been feeling super anxious lately. Thoughts or ideas guys?

Oh and by the way - I am trying to taper down on my Oxycodone usage as I do have OxyContin 80mg pills that my brother and I are splitting since he just got a prescription and is going to eventually try and taper as well as we share the same habit. So we have about 50 OxyContin 80mg pills to deal with here, although selling a few here and there to get some cash back from spending money on buying them off the street.
Well, this past week I have been more anxious than usual and I am pretty sure it is due to the Effexor. Now I have been on Effexor-XR in the past, but I didn't have the anxiety side effects because I was taking medium to large dosages of benzo's and I was also on methadone at the time, so I have no idea whether it did help my bad depression and my general anxiety/panic disorder or what because basically the effexor was being masked my high dosage of methadone + benzo's. I don't even know why I went off of it. But anyway, that was a few years back.
Now I have been clean from benzo's for about 7 months now, except for a few nights I had some Valium a couple weeks ago, but it was very little and only for a few days, or even a day or two. So as of now, I am have been taking Oxycodone daily, I kind of relapsed on that, and my tolerance seems to be going right back to where it used to be (600mg/day), but nowhere near that dosage yet. My daily Oxycodone dosage is usually about 160mg - 220mg daily. But I take Diphenhydramine on a daily basis, right before I dose my Oxycodone, in order to potentiate the effects.
So basically I am wondering if I should be taking the diphenhydramine or not since I now am on 75mg of Effexor-XR. I cannot remember if Diphenhydramine and SSRI's, or SNRI's whatever is a harmful combination? And also if other people noticed increased anxiety from starting Effexor-XR? I have been feeling super anxious lately. Thoughts or ideas guys?
Oh and by the way - I am trying to taper down on my Oxycodone usage as I do have OxyContin 80mg pills that my brother and I are splitting since he just got a prescription and is going to eventually try and taper as well as we share the same habit. So we have about 50 OxyContin 80mg pills to deal with here, although selling a few here and there to get some cash back from spending money on buying them off the street.
