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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

EADD Mephedrone (4-MMC) Megathread v. XIV Pirate Flagship

After a while of using Meph I started to get a slightly dodgy stomach on comedowns, at first it just meant I avoided food for the morning after but eventually I ended up throwing up sometimes too. It was usually worst after binges. I thought it was exclusive to Meph but I had the same happen a couple of months ago after overindulging with MDMA.

Would all seem to suggest body reacting badly to using a little too much. Of course, it might not be the same issue.
 
Ate about half an hour ago, been eating properly all day. I wasn't madly hungry but I've never completely lost my appetite apart from the very first few times I used meph. Got some water on the go at the moment but milk might be nice in a minute.

I haven't actually taken that much recently, maybe 500mg over the last couple of nights and before that I hadn't done meph for almost 2 weeks and any drugs at all for 1. So I'm thinking it's probably down to something else. Hopefully anyway cos it's weird and slightly annoying, don't want to start getting it all the time.
 
Im nearly 100% sure its because your body want some rest and proper food/fluids.

The only weird side effect that i get from meph only are the shockings trough my body, i get them at night when trying to sleep after a heavy session or several days of meph in a row.

Btw. just got a new batch in, damn nice and rushy !:)
 
I eat properly everyday, don't have much choice as I am the chef at both of my houses. Going out for fish and chips now though, yum, fatty.

And it definitely wasn't the meph by the way haha, it was a more everyday problem. It's actually stopped now and I'm feeling quite perky. Got to love being young ;)

I get the shock things too sometimes, only generally when I've been on it for a few days or so like you. Strange, they freaked me out first time but they're not so bad.
 
'Shocks' like a kinda electric shock type feeling in the head? Sometimes with spasms of the body too? That sounds like serotonin depletion. It gets worse if you keep using serotonergics without giving the brain a chance to stock up again and can get really very unpleasant - you can get it with SSRI withdrawal too. Skip the serotonergics for a few days at least and the shocks should go away. Assuming you are both describing what are often known as brain zaps that is. Obviously longer breaks are better if you can take longer breaks.

Sleep paralysis is another common side-effect that a number of drugs - including meph - are known to bring on in some people. Especially after extended and/or heavy use.
 
Like a kind of sudden twitch just as I'm falling asleep. Never had the brain zaps at all, or sleep paralysis. I always sleep pretty well no matter what I've been up to. To be fair I get the random jolt/twitch thing even when I haven't taken anything so maybe it's just a coincidence.
 
If it comes and goes with or without drugs it's probably that reflex action that's supposed to come down to us from when great-great-great-(etc) grandma slept in trees. Stops you from falling from said tree and doing yourself a nasty or being eaten by a sabre-tooth tiger and so on apparently. Quite annoying when you really do want to get to proper deep sleep with a nice soft springy thing fairly close to ground level to lay on and nary a sabre-tooth in sight, mind.
 
Haha Shambles. I often look out my window and see marauding sabre tooth's in my garden - you mean you don't? Not near my sleep-cave though, I'll admit.

I do get it without drugs and got it before I started taking drugs at all but it almost always get it after a few days on meph (not with coke, weirdly). Why would that be? It can't just be a coincidence.
 
Seretonin related im reckoning. and no it isn't weird you dont get it from coke, cos coke doesn't effect serotonin. After bashing meph or MD i get the same thing. also got it before doing drugs, but less often
 
Cocaine does affect serotonin but differently to how meph or MDMA and similar drugs do. It doesn't dump loads all at once but it is a reuptake inhibitor which means you still end up with increased serotonin levels - that's why it's so much more obviously euphoric than more focussed dopamine reuptake inhibitors like methylphenidate, ethylphendiate, desoxy and MDPV. Coke is doesn't drain heavily serotonin levels in the way that serotonin-releasers like meph and MDMA do so you don't get the same type of crash afterwards with the potential (or likelihood if you're doing enough often enough) of brain zaps and general spazzing about a bit and feeling horribly depressed.
 
Oops, my mistake. either crossed wires or read some bollox info recently. maybe both knowing me
 
The emphasis is definitely on the dopamine side of things with coke but if it was solely dopamine (and noradrenaline which is the third part of the holy triumvurate) reuptake inhibition it would be weak MDPV - basically Ritalin. Not literally of course but subjectively it would be a lot closer to the hyperfocus, OCD obsessive and looming psychosis end of the spectrum than it already is. The bit of serotonin bubbling away at the same time gives it the distinct euphoria which DRIs/DARIs (MDPV and so on) lack. Or do very, very differently anyway.
 
Shambles said:
DRIs/DARIs (MDPV and so on) lack. Or do very, very differently anyway.
Click to expand...

I'm a bit confused... DRI is obviously Dopamine Reuptake Inhibitor but what is DARI? You are the second person I've seen to say that I think.

I assume that would stand for Dopamine & (Nor)adrenaline Reuptake Inhibitor, which is more correctly a Norepinephrine-dopamine Reuptake Inhibitor. NDRI.

Just curious as to where you found that abbreviation since it doesn't seem to exist.
 
Hmm... you are correct it appears. It is a commonly used term for what are presumably just DRIs then - I'd always just assumed it was a common alternative and hadn't really looked into it. As you say, technically they are generally dopamine and noradrenaline reuptake inhibitors so I'd just assumed the 'A' was for the adrenaline that breaks down to noradrenaline. It does make sense that it should but you are apparently correct that it is not actually a recognised term - not on the upper part of the top page of Google anyway (I put extensive research in at all times naturally). NDRI got that job to itself it seems - wonder why DARI (usually DRI/DARI whenever I've seen it used) is so widespread then? Thanks for the correction anyway - always good to know when you're using bad information or terminology. Banished from my vocabulary.
 
Shambles said:
The emphasis is definitely on the dopamine side of things with coke but if it was solely dopamine (and noradrenaline which is the third part of the holy triumvurate) reuptake inhibition it would be weak MDPV - basically Ritalin. Not literally of course but subjectively it would be a lot closer to the hyperfocus, OCD obsessive and looming psychosis end of the spectrum than it already is. The bit of serotonin bubbling away at the same time gives it the distinct euphoria which DRIs/DARIs (MDPV and so on) lack. Or do very, very differently anyway.
Click to expand...

Best fact I've heard for a while, I knew coke affected serotonin as well but didn't know any specific detail about it. Interesting. We so need an EADD coke thread, drone is so last year ;)

I have nothing interesting myself to add, feel rather odd but not in a bad way sooo uh, continue. *wanders off*
 
When I see something I don't understand, I instantly Google it. As you can imagine, I Google things rather often. :D

Right. It seems that the 'A' stands for adrenergic, I think. That's about as far as my understanding is going to go right now... or what Whoremoaning said.

Some book or journal (trying to relocate source as we speak) had this... but they might have had it wrong:

dopamine and adrenergic reuptake inhibitor (DARI)
Click to expand...

Which is a rather complicated way of saying a DRI & ARI, which is actually just a NDRI. My brain hurts. I'm quite possibly talking utter shite.
 
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