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DXM to DMT with -- thoughts about exploration of psychedelics and other substances...

bluedom

Bluelighter
Joined
Oct 29, 2010
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246
My background is below. My question is that I'm now tempted to try the Psychotria viridis (chacruna) and Diplopterys cabrerana(chaliponga) with DMT in it that I have from a while ago. The only MAOI I have is seligline and I'm wondering if anyone has tried it with this and if it has worked. Previously I have tried a Ayahuasca brew before (with harmaline) and had a light DMT experience: my psychedelic experience was more like an oil painting and sunnier. I don't like to smoke stuff so it has be a brew. My worry is that seligline is a MAO-B inhibitor ibut I don't see a reason why it should work even though the harmaline compounds are MAO-A inhibitors. If I take make a brew of these two plants (I have about 2 grams worth total) and then take it with seligline will the DMT experience come through or will it be wasted?

As an intense kind of person I've had a tendency in my life to explore one aspect of something and sometimes excel at it (fortunately I seem to be able to complete projects, not all of them but way more than enough so that I'm not just dabbling in too many things) and then move on to something else. As an academic, I can just say "learning" and then everything is accessible to me.

I've also explored psychedelics and mood altering drugs in the same manner. I usually intensely use one substance for a while and then move on. I've never had problems with this except for alcohol which was a mistake that I realised only on my recent intense DXM trip (I was actually trying to explore my psyche with alcohol and while it may have had some limited effect initially that soon went away as the physical addiction developed). I made it to the third plateau and perhaps sigma also since I redosed about 8 times over one week and always twice with hash oil (only one day were the third plateau doses that seemed to really go beyond most third plateau descriptions and had elements of the plateau sigma in it as per the DXM FAQ.
 
My question is that I'm now tempted to try the Psychotria viridis (chacruna) and Diplopterys cabrerana(chaliponga) with DMT in it that I have from a while ago. The only MAOI I have is seligline and I'm wondering if anyone has tried it with this and if it has worked. Previously I have tried a Ayahuasca brew before (with harmaline) and had a light DMT experience: my psychedelic experience was more like an oil painting and sunnier. I don't like to smoke stuff so it has be a brew. My worry is that seligline is a MAO-B inhibitor ibut I don't see a reason why it should work even though the harmaline compounds are MAO-A inhibitors.

I have read this part about 5 times now and i still dont understand what you are asking.

No it wont work, and you already said why it wont work, you even said that you dont see a reason why it should work. So why do you ask?

MAO-B metabolizes phenethylamines and dopamine. Theoretically you could increase the selegiline dosage past the MAO-A threshold and then drink your brew, but i wouldn't and i dont think you should either. Mainly because it binds irreversibly.

Find a non-dirty selective reversible MAO-A inhibitor and youre good to go
 
Well, logic isn't always right when it comes to biology in my experience. But aside from being flippant (sorry), I've had a mild DMT high with pure DMT alone without a MAO inhibitor by really pushing the levels of DMT in the brew (meaning I drink a lot of it) so some of it makes past the BBB without getting broken down (my guess is that I oversaturated the MAO-A). I was wondering if anyone had had experience with seligline helping at all in this process, especially those who have to take seligline regularly and have used DMT---have they needed to use less of the MAO-A inhibitor for example. I'm just a bit concerned about MAO inhibitor cross reactivity.

I'll take your advice and the advice of the other poster to buy the B. caapi and postpone this experience for a while. I just wanted some confirmation.

Aside from that, what about the mixing of the DXM and DMT in terms of psychic exploration, meaning I do DMT once, and then DXM the next weekend, and switch it around rather than just sticking to DXM alone? Right now, I feel that DXM, DMT, and both with hash oil would be good combinations to keep trying but I've not had enough experience with DMT alone to say this is a good idea or not. If someone had asked me this question, I'd say you definitely need to have experience with DXM before you start mixing stuff up. With DMT I've had limited experience and it has all been rather mild/benign so I feel I can handle this but is this the kind of thing that can come and whack you unexpectedly? There's a trip report on Erowid where the person almost exactly arrives at this combined combination but totally by accident (i.e., the cannabis has been soaked in DMT (due to reusing containers I believe) and the person takes a potent hit of it by accident while on DXM and feels it could've been gone really bad but someone was watching out for him, so this person actually had a good experience with it. I'm actually proposing separating the two a week or so.

I have read this part about 5 times now and i still dont understand what you are asking.

No it wont work, and you already said why it wont work, you even said that you dont see a reason why it should work. So why do you ask?

MAO-B metabolizes phenethylamines and dopamine. Theoretically you could increase the selegiline dosage past the MAO-A threshold and then drink your brew, but i wouldn't and i dont think you should either. Mainly because it binds irreversibly.

Find a non-dirty selective reversible MAO-A inhibitor and youre good to go
 
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