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Stimulants DXM to breakdown stimulant tolerance?

sean107

Bluelighter
Joined
Oct 7, 2010
Messages
1,323
Location
Where gnomes reside.
Can anyone please explain how it is that dxm can breakdown/prevent tolerance to stimulants, along with other drugs, and with that what dosage of dxm and how frequently, to get the prevention/breakdown of stim. tolerance.
 
DXM is an NMDA-antagonist.
to my knowledge, stimulants agonize the NMDA receptor, thus causing tolerance.
so throw in an NMDA-antagonist and it essentially reverses tolerance.

NMDA-antagonists up-regulate DA receptors too right? someone correct me if im wrong :\
 
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