Dxm and welbutrin

[Pineappleexpress42]

so im on 75mg welbutrin and 50mg seroquel i did dxm first time a few days ago 130mgs felt really cool but worried to do again because of possible interactions with welbutrin and dxm?

 

[AlphaMethylPhenyl]

There isn't really any pharmacological cumulative action

 

[Thorns Have Roses]

Bupropion inhibits CYP2D6 so you might have a less pleasant experience due to a higher amount of DXM relative DXO in your system. Also combining norepinephrine reuptake inhibitors can lead to much unpleasantness.

Keep your doses low and it should be fine.

 

[Druidus]

I've seen people do DXM on bupropion before, and I've seen that the subjective effects are stronger and less enjoyable.