Kratom DXM and kratom

[SotPoker1012]

DXM seems to potentiate most opioids. I know kratom is a special case, but I can't seem to find much about this combination.

1. Does DXM potentiate the opioid effects of kratom?

2. Kratom has additional serotonergic properties. Do you think there could be any bad interactions regarding that?

3. Has anyone actually tried it?

 

[daturetard]

Used to be a favorite of mine. Definitely potentiation ime. Dxm I think potentiates all opioids, because it has opioid properties in and of itself. Combined with nmda antagonism its certainly gonna get you higher, but I dont know if it actually makes other drugs stronger or just adds to their effects.

 

[chippermonk]

I've never tried them together and really have no interest. Seems like a way to screw up the high and maybe be dangerous, but someone else would know more than me.
However here is a resource I found that might be useful. Among other things, the website talks about the safety of interactions between kratom and a wide number of substances, so I hope this qualifies as helpful. DXM is one such interaction discussed.
It sounds like the real issue is that of their mutual effects on CYP2D6. Kind of complicated.

DXM (Dextromethorphan) & Kratom: How Do They Interact? - Kratom.org

DXM is an active compound in over 100 medications. Are you wondering if you can take kratom while on DXM? Learn all about their interactions here.

kratom.org

 

[tarman]

It's a good combo but I haven't pushed its limits. So that is to say the most I've ever taken is 30 ml of of a doxylamine and DXM combo with kratom. One thing I do like is it seems to have an immediate effect on the 'need' for your next dose of kratom. In other words if you take it the night before, you don't feel like you need your morning dose of kratom. Your mileage may vary. But it was nice and it helped with sleep, and maybe that was partially due to the doxylamine but I feel like the DXM helped.