mrflowers00
Ex-Bluelighter
could doing oxycodone and alprazolam be lowering my sex drive
Naturally occurring opiates (endorphins) diminish testosterone levels by inhibiting both hypothalamic gonadotrophin releasing hormone production and testicular testosterone synthesis. Heroin addicts treated with a single daily dose of methadone and nonaddicts receiving continuous intrathecal opioids quickly develop low luteinizing hormone and total testosterone levels. A similar pattern was sought in men consuming commonly prescribed oral opioids. Free testosterone (FT), total testosterone (TT), estradiol (E(2)), dihydrotestosterone (DHT), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) were measured in 54 community-dwelling outpatient men consuming oral sustained-action dosage forms of opioids several times daily for control of nonmalignant pain. Hormone levels were related to the opioid consumed, dosage and dosage form, nonopioid medication use, and several personal characteristics and were compared with the hormone analyses of 27 similar men consuming no opioids. Hormone levels averaged much lower in opioid users than in control subjects in a dose-related pattern (P < .0001 for all comparisons). FT, TT, and E(2) levels were subnormal in 56%, 74%, and 74%, respectively, of opioid consumers. Forty-eight men (89%) exhibited subnormal levels of either FT or E(2). Either TT or E(2) level was subnormal in all 28 men consuming the equivalent of 100 mg of methadone daily and in 19 of 26 (73%) consuming smaller opioid doses. Eighty-seven percent (39 of 45) of opioid-ingesting men who reported normal erectile function before opioid use reported severe erectile dysfunction or diminished libido after beginning their opioid therapy. Commonly prescribed opioids in sustained-action dosage forms usually produce subnormal sex hormone levels, which may contribute to a diminished quality of life for many patients with painful chronic illness.
- I smoke between 5-12 Hand rolled cigarettes a day
i have been on subutex for about 5-6 Months now (4-6mg snorted daily + used numerous drugs in the past 6 years) iv been fine getting erect for most of my life (and the Subutex period) until these past 3 weeks or so. I am using my subutex + occasionally a low dose of a benzo daily, even throughout my Subutex period Ive always been a bit of a horny bastard, sometimes being up for having sex up to 5-6 times a day (sorry if that's too much detail) BUT now im worried, last time I was erect (I wasn't even fully erect) and actually came, was about 2-3 weeks ago..Now i simply cant get erect, and if I do its only for a few secondsim very worried about this and it saddens me, im also a bit of a hypochondriac (if that's how you spell it, I think TOO MUCH!) which doesn't help matters.
So PLEASE could someone help me? i would be very very greatful. Is this permanent damage? will my libido increase when I get clean? (I am doing a Detox in a few weeks)
Also here are a few factors which Im not sure contribute to my erectile dysfunction but I thought I would list them to help give a better analysis if possible!! (obviously if it continues I will go to the doctor) but at the moment im very worried and any info would be truly golden:
- I do go to the Gym and I do take supplements such as Tribulus, (Jack 3d very occasionally) Glutamine + a range of different vitamins (no roids if your wondering)
- Subutex 4-6mg nasal daily as said before
- I smoke between 5-12 Hand rolled cigarettes a day
- I drink occasionally
- I take benzos occasionally
Please Help!
Best Regards BL
No matter what drugs ive taken in my life, ive always been in the mood to have sex with my girl............actually, when on opiates, I get more horny when we are fooling around & having fun.
As for erectile problems, only coke has done that once to me & I never mixed stims with sex as much after that. never had a problem with opiates, in fact, its the opposite for me, opiates are awesome during sex.