Drugs affect everyone different but I am ODD..

[dugefrezh]

Drugs have always affected me differently, esp the people i hang with. for my smaller size one would think i would naturally be a lightweight. but its the opposite. I need a truckload of meds to get "high". I am on scripted meds, Xanax since i was 19 (10 years) and recently (3 months ago) Adderall 30mgs 1 time a day for inattentive Adhd. I had started going to my shrink becuase i was becoming a recluse. I couldn't leave the house without panic-ing. People scared me. Driving scared me. Alot of things scared me. I was initally put on klonopin .5 2/day for a couple weeks and it didnt help all that great. next time i saw my shrink he started me on xanax 1mg 3times a day. now 10 years later I'm at 2mg 5times a day. and even to me that seems like a truckload of xanax. but it helps. and now with the adderall I can even talk to people I dont know, approach a girl i find attractive and form relationships that once were never possible. I do not get the "speedy" effect from my adderall, but it does seem to curb my appetite and keep me up at night. which may I say I HATE. thank god for marijuana. or else i would have stopped the adderall.

But what i do not get is why on earth anyone would want to take a xanax or an adderall to get high? there seems to be no high for me, never was. even when taking more then prescribed to experiment. and then there is alcohol.. i never was a drinker, hated the taste back in high school, beer or stuff like mikes hard would just kill me by the bloating and upset my stomach. i figured it was the carbonation. also stopped drinking soda at a young age, like 16 for the same reason. it just upset my stomach.

but still to this day, when i go out, alcohol again is weird.. i cannot seem to get drunk without binge drinking. Hard liquor is like water to me. no burn. one, two, three shots of it is like nothing. hence why i do not drink. it seems pointless. no matter if its vodka, tequila, whisky, beer, wine.. i just don't feel it like other people. Is it the amount of xanax i am on that prevents the drunk feeling? but like i did say Binge drinking WILL fuck me up. sloppy drunk, cant walk, blackouts, and vomitting. and of course a nasty hangover the next day. This is prob why I do not drink.

BUT on the other hand, OPIATES. omfg they are like heaven on earth to me. my first taste was at a young age. thanks to erowid. it was my bible as a kid, i was infatuated with drugs. without ever doing them, i pledged to try every single one at least once. still haven't gotten thru all the majors. but i educated myself on every single one for years. even this site i have been lurking, reading posts for a decade or more. so anyway back to opiates. my first taste was 2 5/500mg pills of this hydrocodone stuff i read about. seemed like an appropriate dose for me at the age of 14. it was the best blissful feeling ever. didnt touch any opaites for years after. but time caught up with me and living in the heroin meca of chicago. i studied up on it and knew its just another opiate. just stronger. alot stronger. but railing that powder my first time got me. to this day i still do it. now i just graduated to mainlining it. which i promised myself id never do but my cousin got me to try it and snorting was no longer an option. Ive been on suboxone on and off. but it doesnt seem to work for me like it does others. I can take my 1/4 film in the morning.. get dope in the evening and slam it and be high as fuck. just one bag too. since my current relapse, i can do one or two bags and not need anymore. then i go a couple days without the subs and it seems like i need more dope to get high. same batch. i can hold on to a 12 pack for a week or so and do it intermittently but if i take a small dose of sub after w/ds come on a little, the next 12 hours i do some H and bam one bag will get me higher then the 3 it would take the day or two before. I just think its very odd. Would there be any explanation as to why this happens to me?

 

[pasha]

Just to clarify and allow you to get more accurate responses, are these the questions:

"Why do I get higher on heroin plus suboxone more than heroin alone?"

"Why do people abuse amphetamines for euphoric effects?"

 

[dugefrezh]

Yes why do i get higher on heroin when subs in my system then alone?

and Why or how do ppl abuse amp for euphoric effects?

and Why doesn't alcohol get me drunk like normal people? <~~~ i know that ones a little off the wall

 

[dugefrezh]

because i don't know who is actually a normal person...

 

[pasha]

Well, the first question I saw a response that could explain this from another member a few weeks ago. Something about the naloxone potentiating opioids. Shoot him a PM if you want more explanation, his username is serotonin101.

The second question in regards to amphetamines, they are dopaminergics, which makes them euphoriants. The end result of most deeply euphoric drugs is a flood of dopamine in the reward circuit. Those include opioids and amphetamines. I think the reason you prefer opioids of amphetamines is you have anxiety issues, and amphetamines can worsen them, opioids usually resolve them.

There's really no specific reason I can give you on why you don't get drunk. Many of my friends are the same way. Everyone is drunk at the end of the night, they've literally drank a few liters of hard liquor, and they look just fine. Maybe you fall into that category. Consider yourself lucky though because alcohol is a lousy drug.

 

[Midazle]

Theres a bunch of people who find opioids to be exclusively the best choice for them...its all about your personality really. I don't find any fun in alcohol in sedatives abuse wise either and recreational adderall makes me tweak BAD..

 

[dugefrezh]

Well, the first question I saw a response that could explain this from another member a few weeks ago. Something about the naloxone potentiating opioids. Shoot him a PM if you want more explanation, his username is serotonin101.

that could make sense with my needle fixation now i will sometimes shoot the subs but in very small doses like 1/8 of a 8mg film when dope is not avail..

 

[pally pete]

I think the reason you prefer opioids of amphetamines is you have anxiety issues, and amphetamines can worsen them, opioids usually resolve them.

As someone who suffers with severe Anxiety I can agree that Opoids are far more suitable than Amphetamines. But as far as I was aware, Opoids do not resolve the issues, they just mask them.

 

[lifeisflyingaway]

Just like you i pledged to atleast try every drug atleast once. In the beginning i never liked "downers" and only liked uppers like meth, ecstasy, or amphetamines. They made me talkative, euphoric and speedy and of course a bunch of negative side effects as well. Although majority of these days i'm sober, i have came to the realization that i like opiates which i used to hate, and have only done heroin once and felt more euphoria and butterflies all over my stomach from smoking it which i didn't feel from other drugs, so hopefully i can stay away from heroin. People take amphetamines for a variety of reasons including helping them to concentrate and stay up longer to be what they call "productive". And i have real bad anxiety, but don't plan to become addicted to benzos or even take them as prescribed because i have heard too much negatives about benzo addiction, and withdrawals. I used to think alcohol was the most boring drug, but i unfortunately do like it until i get hungover though. I don't think i answered much because i couldn't figure out much of the questions you had but i hoped i helped with a little.

 

[hatrix]

In the beginning when I had only tried uppers, name mephedrone, I thought it was the most wondrous drug anyone could imagine. I still probably is a great drug, but I can no longer find it, so oh well guess. The search has always been on since for something similar.

Now after being hospitalized from a stimulant induced panic attack from a single small dose of 4-FA (along with being diagnosed with stimulant induced hypokalemia, which can be deadly), and having another panic attack from a single dose of a-PVP (30mg insufflated), I've been prone to stimulant induced anxiety every since. I always get it to some extent, more so and sometimes a lot on the comedown. I constantly aware of my heart beat, and am always checking to see how prevalent my veins are my in arms as an indication of blood pressure.

Most of those times where when I had never even tried a benzo. These days I'm prescribed benzos monthly for generalized anxiety disorder along with more rare panic attacks. I'm on Clonazepam right now, 0.5 x30.

Benzos make stimulants almost not a worry when it comes to the comedown. Yea, I still worry about my heart rate and blood pressure during the effects, but in the back of my mind I know I have the safety of a benzo to help me if things get to out of control anxiety wise. And also to help me get to damn sleep !

When I first tried opiates forever, I fell in love with those too. 15mg of hydrocodone and I was as high as a kite. Sedated with lots of euphoria.

I still continue to do them to this day though. Today I've taken a total of 60mg of ritalin and 10mg of Adderall XR crushed up, all plugged.

However, when I first tried opiates, hydrocodone 15mg , I fell in love with them. Complete relaxation, euphoria like no other drug, sedation that was always welcomed but plenty of energy if needed, a feeling of pure bliss (unlike MDMA, a different kind of bliss), the opiate warmth that is loved so much, and to top it all off NO HANGOVER. That's right. ZERO, ZILCH, NINGUNO. Nothing but falling asleep peacefully while usually still high and having some great sleep.

This is still my current case with opiates today. No effects are different. dosages are slightly increased, but all the effects remain the same. I still choose to do amphetamines and other stimulants when I have them though. Sometimes the same drug bores me when I take it over and over and the comedown is undesirable, so I take a break from stimulants and enjoy things such as opiates, benzos... though not so much in a recreational way, and MXE.

MXE is still me DOC.

 

[dugefrezh]

About the subs, i was wondering could the bupe actually be helping me get higher on smaller doses? like could it just be blocking say 30-40% of my opiate receptors due to the very low and infrequent dosing? then causing the remaining receptors to just become stronger in a sense? i never get to do H but maybe 1 or 2 times every week or two though. i tend to spend the rest of the time plucking peices of a 8mg film and making it last days. this way i get to trade half the box for dope. and im totally getting ripped off too on the deal but i dont care if i get 2 or 3 bags of some really good dope for 10 subs. what can u do? i take what i can get. I cannot go to the westside or southside do to horrible luck with reverse racial profiling by police officers. they look at me and im pinned. funny thing is i look not of a dope fiend, not in the slightest. clean cut attractive excellent body weight and i look 10 years younger that what i really am. i don't belong in those area's without getting noticed. ive been to cook county twice and never going back. fool me once shame on you fool me twice shame on me fool me the 3rd time then im just insane.

 

[hatrix]

Here's the thing about suboxone/subutex, (that I find my self repeating a lot )...

They both contain buprenorphine. The naloxone in suboxone is completely negligible, it does nothing what so ever. So just forget it's even there.

When you take buprenorphine in doses <2mg, it's active metabolite norbuprenorpine, which is FULL agonist, attaches to your receptors. HOWEVER, when you dose 2mg+, norbuprenorphine is no longer active at your receptors, buprenorphine with its incredibly high affinity takes over and completely knocks of the norbuprenorphine.

That is, for RECREATIONAL USE, doses <2mg are the most preferred. More is less, yadda yadda. Norbuprenorphine has more euphoria and is a full agonist. A full agonist is always going to have better opiate feelings than a partial agonist. For someone with little tolerance, a single 8mg Suboxone strip or Subutex pill can go a long way.

Something to keep in mind. I'm still not fully knowledge on receptor affinity and blocking, along with the more advanced μ-opioid receptor discussion, but I'm pretty sure that buprenorphine doesn't start blocking any other opiates until at least 4-6mgs is ingested. I'm going to need someone to back me up on this though or correct me if I'm wrong.

 

[pasha]

As someone who suffers with severe Anxiety I can agree that Opoids are far more suitable than Amphetamines. But as far as I was aware, Opoids do not resolve the issues, they just mask them.

Yes you're correct, by resolve I meant temporarily resolve, which you could equate to masking them, putting a band-aid over them, or treating them. If you take resolve in the sense of curing, than that's not true to any medication as anxiety and/or depression have no medicinal cure.

 

[hatrix]

Yes you're correct, by resolve I meant temporarily resolve, which you could equate to masking them, putting a band-aid over them, or treating them. If you take resolve in the sense of curing, than that's not true to any medication as anxiety and/or depression have no cure.

Yea by that sort of thinking, you could say benzos are like a band-aid too. While they mask the symptoms of anxiety and make a user feel calm and/or normal, they don't cure anxiety and can often times bring it back worse than before when abused.

 

[blight12]

Well bezos are no fun for me and many others and Adderal is a terrible example for making an accurate judgements on amps. Dont take the stuff now but proper meth would be difficult to find fault with in comparison to adderal. Dosage also plays a big part here in your effects so far im sure since pharama amp doses are low and hardly recreational imo and the effects might be more subtle for a drug thats often subtle already.

Booze sucks in general and opiates might be your thing and certinally better then adderal crap and benzos, no surprise there. I also need greater dosages for most things but the effects are as expected and normal in most cases.

Also keep in mind it takes some time to identify effects and see the benefit with some things and stims for sure due to their subtle method of action and they are horrible for me personally in low normal doses and light and day different in effect with modified dosage.

Also some of your issues sound like anxiety related problems so maybe thats something to consider and treat as appropriate, if its the adderal i would not be surprised due to the anxiety effects i get on similar doses.

 

[onetwo]

I personally take (not prescripted) amphetamines everyday because it's light and extremely helpful. I can pay great attention to things, I am always a million times more motivated, more talkative, eat less (actually a problem), the cigarettes feel way better (and so does the occasional J), it's more warm, happy, cheery, I could go on forever. It's not so much that I often go snort like 80mg of amp for a high or anything, I just like to take them everyday to just make my life more awesome.

 

[blight12]

That pretty much sums up the effects and fantasies of potential for greatly improving life in every way and for as long as possible. A convincing argument and difficult to argue with no doubt about it. I cant find fault with taking the chance. Drugs more often then not need to teach their invaluable but harsh lessons through experience. Been worth it in my opinion for sure but its not pleasant process.

 

[Z3R0S]

drugs jus fuk u up.... they change people, whether they want to admit it or not... i finally do

 

[dugefrezh]

drugs can fuck a person up mentally yes, but what about the people who are mentally fucked up to begin with who use drugs to cope with life.. yes there are other ways of coping with a shitty life but drugs can be an easy temporary fix to them. and it may be the only way they've known how to cope.

 

[Venrak]

^Drugs can be used as a temporary fix, but it is only temporary if real work is being done to actually correct the problem. If you don't build yourself a foundation to stand on when the drugs are taken away, you are never giving them up. Your will to live is too strong to let go of the main coping mechanism you have.

That is a big problem with anti-depressants and anxiolytics; Doctors throw around scripts but there is rarely any talk therapy, no cognitive behaviour modification to actually correct the problem instead of just treating the symptoms.