Drug designs. (MedicinalUser SAR thread)

[MedicinalUser247]

LOL ! Well there are some explosives that can also be used as food.

 

[MedicinalUser247]

I call this one MD-Deluxe. https://ibb.co/ZHyqf11

 

[MedicinalUser247]

I call this one Astro-K. https://ibb.co/xMs0z7V

 

[MedicinalUser247]

I call this one Ketofent. https://ibb.co/8B09gs2

 

[MedicinalUser247]

I call this one Cyclofent. https://ibb.co/0sxbFHC

 

[MedicinalUser247]

I call this one MD-S2. https://ibb.co/1bfdhsW

 

[MedicinalUser247]

I call this one MD-S-Squared. https://ibb.co/B492mxd

 

[MedicinalUser247]

I call this one MD-OH-Squared. https://ibb.co/8jSLfDK

 

[Smyth2]

Just having a phenol/thiol group on the aromatic ring is likely to be too polar. For this reason they normally occur as the methyl ethers.

 

[MedicinalUser247]

I call this one MD-K-PEA. https://ibb.co/QC4XzQ5

 

[MedicinalUser247]

I call this one 2C-MDAI. https://ibb.co/GnzJ4K7

 

[MedicinalUser247]

I call this one 2C-SSAI. https://ibb.co/xhz9HmM

 

[MedicinalUser247]

I call this one 2C-NSN-AI. https://ibb.co/nRk0Bsp

 

[MedicinalUser247]

I call this one 2C-NON-AI. https://ibb.co/7Ytf2JD

 

[Smyth2]

Methamketamine hosted at ImgBB

Image Methamketamine hosted in ImgBB

ibb.co

Tker said something about a drug called "Methamketamine".

 

[MedicinalUser247]

I call this one MDMA-K. https://ibb.co/41cJzSS

 

[Smyth2]

I call this one MDMA-K. https://ibb.co/41cJzSS

I can't guarantee it but i'd expect this to be a realistic design. It looks like a so-called bifunctional molecule.

xtc is weaker than speed though so i'd be tempted to see what it functions like w/o the methylenedioxy group also.

 

[Smyth2]

I was thinking of "methamketamine" again and came up with a second structure that occurs when you change the synthesis approach:

Methamketamine2 hosted at ImgBB

Image Methamketamine2 hosted in ImgBB

ibb.co

 

[MedicinalUser247]

Here's the other version of MDMA-K that I didn't post. You see when you add the extra methyl it weakens the bioactivity of the structure. Making it target less of the A-G coupled protein receptors. https://ibb.co/QbzJxB2

 

[Flynnal]

Imagine the sodium salt of a C-2 sulphur substituted version of vinylbital. I bet that one would knock arse right over. There is actually a thiobarbiturate version of Seconal and Nembutal, so having one of Optanox would be interesting. Strangely enough I've never seen a thiobarbiturate version of Amytal, which makes me wonder what happened there. My guess is likely because they already had Surital and that having one anaesthetic barbiturate in their respective market was enough for them.