N&PD Moderators: Skorpio | thegreenhand
Looks like it could be finicky near the end, but I like what's going on here.This Synthetic Outline Cleverly Avoids The Harsh Reaction Conditions (either H+ or -OH with heat in reflux) Which Could Destroy The Acetal But Which Are Required For The Reaction Of An R-Cyano Functional Group To An R-CO2H Functional Group.