Dph and Dxm

[Lolitadahmer]

I've been taking dph for a while but I want to try something new, I have Dxm but I'm on 40ml of Prozac... How much dxm is safe?

 

[oar9fi]

Many people have had bad experiences requiring hospitalization from combining DXM with SSRI's. I would say that any dose of DXM high enough for dissociative effects would also be enough to cause a bad reaction. Serotonin syndrome is NOT fun. Wait until you're off the Prozac if you really want to try DXM.

 

[Black Rabbit of Inle]

Don't do it. DPH and DXM are a good combo if you weren't on Prozac.

[From The Dextroverse:]


DXM should never be taken while on medications such as MAOIs and SSRIs, this may interact with DXM to cause serotonin syndrome. This condition, although rarely fatal, is not terribly pleasant. Some of the symptoms of serotonin syndrome include muscle rigidity, confusion, diarrhea, incoordination, low-grade fever, sweating, muscle tremor, mania, agitation, exaggerated reflexes, and nausea. Some drugs to avoid taking while on DXM are:

• phentermine, fenfluramine, phen-fen (diet drugs)

• fluoxetine, tricyclics and lithium (SSRI antidepressants)

• terfenadine (SeldaneTM - prescription antihistamine), & possibly other non-drowsy antihistamines, such as ClaritinTM and HisminalTM (these can cause heart irregularities)

• antidepressants Desyrel (trazodone) & Serzone (nefazodone) (Possible liver damage)

• some SSRIs such as bupropion (WellbutrinTM) can give a prolonged (3+ day) hangover.

• also, cigarette smoke might be considered an MAOI, which may increase unwanted side-effects

• MDMA (extacy), while it isn't a MAOI, it should be avoided with DXM (possible heart problems)

• opiates can cause a fatal overdose when mixed with DXM.