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DOX compounds long term effects?

headdah

headdah

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Recently me and my mates we have all moved on from pilling, aciding, to DOI'ing.

gotta love the 18hr+ trippings on them. There isn't much study done about it.

Can anyone tell me their experiences on doi's etc. perhaps long term user side effects etc?

I've notice some random colours/fluffs/dots appear on walls etc during the week sometimes. other than that nothing.

Also anyone else out there started to love their doX's ? :)


cheers
 
Only done DOC once and it was good, not as intense or mind expanding as acid but probably more fun for partying. Dont know if ill use it too often though as its pretty exhausting, just a bit too long for my liking but thats nothing benzo's cant fix.

Not sure of any long term side effects but its supposedly pretty safe but I guess only as safe as an RC could be. Who knows we could all end up growing another arm or a new ear in a few years, noone knows but as long as you use it responsibly then you probably wont encounter too many problems, just be weary that these things havent been proven safe so its all in your hands whether you want to take the risk.
 
DOC not as intense as acid? How much did you have? 4mg beats most tabs i've ever had.

How can a crazily strong psychedelic stimulant not be intense?

%)
 
word, doi is just as intense as acid, just less mindfuck which i like.
a hell lot more visuals and bright colours that i enjoy.

add nos to the menu, then BOOM. its a fantastic adventure :)
 
You will probably get more/more useful responses in Psychedelic Drugs, I'll move this there for you where it may get merged into a Big & Dandy thread.

There isn't much research into these compounds, so your going to have to go by user's reports of long term side effects, be aware though that they quite probably have used many other substances that may have causes these long term effects.

AusDD===>PD
 
Why would you want to smoke them? Yes, you should be able to. They won't give you a rush or come on fast, though, it'll still take an hour or three to kick in.
 
I'm not exactly sure all the details about this, but doi is a pretty heavy (70%?) HT2B agonist, which makes it bad for your heart. This is why if you want to decode it: "...overexpression of the 5-HT2B receptor in the heart leads to compensated hypertrophic cardiomyopathy associated with proliferation of the mitochondria."

and "cardiac hypertrophy is a thickening of the heart muscle (myocardium) which results in a decrease in size of the chamber of the heart."

So that's probably not great for you, but who knows how bad that really is.
 
the DOx compounds could also induce more long term tolerance than other psychedelics like psilocybin or LSD.
 
Modulus said:
DOC not as intense as acid? How much did you have? 4mg beats most tabs i've ever had.

How can a crazily strong psychedelic stimulant not be intense?

%)
Click to expand...

Sorry to backtrack here but I gotta answer a question when asken unlike someone I know who never answers my questions and it pisses me right off lol.

I only had about 2.5 mg, maybe even less so thats probably why it wasnt as intense as you say, but I find acid and tryptamines alot more weird, interesting and visual than I do phens, I think the only phen ive ever had that came close to the intensity of acid is 2C-T-7 which im still unsure as to whether I like it. LSd is the bes psychedelic drug I could ask for and ive tried quite a few, but different stroked for different folks as always.
 
Yes, I certainly do love DOXs, although my favorite is DOC, not DOI. As for long-term consequences, unfortunately little is known. I can personally attest to the fact that they create a more severe long-term tolerance to all serotonin agonists (read: most psychedelics) if you use them regularly.
 
I hate them, they produce enormous anxiety for me, and gave me my only really horrible bad trip. To each their own, though.
 
One of my best trips was on DOI. I loved it. I went through 100mg of it over about a year and never had a bad experience with it. At the weakest it was slightly mind-altering and stimulative, and at the strongest it rivaled a moderate-dose acid trip.

I haven't had any serious long-term effects that I've noticed. I've moved and no longer have sources for anything, so I haven't tripped since May (when I used the last of my Iprocin to give my girlfriend her first trip-- very cool time!). The only lingering thing I've noticed is that I sometimes get twitches in the muscles at the corners of my eyes. I've checked the mirror when this happens and it's not visible, so they're slight, but it's just enough to distort my vision for a second.

I went through about 2 years of very very heavy RC use (sometimes abuse, tripping 2-3 times a week), and if this is the only side effect I have for all the good times I had, then fuckin' A! Who knows, maybe we'll all drop dead of cancer in 20 years, but I'd rate the odds as slim. Sasha and Ann are fine, and that's good enough for me.

The only other thing I've noticed is that I have a tendency to ramble and generally talk shit, but I'm not sure that's drug-related.
 
im one of hedahs friends....and i do have to agree, doi and nos work great togther....we had no idea where loops began and ended and during the day...colours changed dramaticly when you took a NOS in...intense?

all i have to say...is do it with people you like lol

xoxo see u bye crack brother
 
DOI is wacky material. Always has a brutally depressing come-down when there's nothing to be sad about. Highly stimulates CNS for me. Like my nerves are just charged with electricity. Muscular pain and a tightening feeling in my airway was something I couldn't really ignore. When I combined 2.5mg of DOI with 20mg of 2C-I about two years ago I remember it being remarkably hard to inhale. Visuals sure were unfathomably gorgeous though.

For me at least DOI has very strange effects. Had me experiencing symptoms of OCD and my humor was extremely sinister. For example I recall laughing hysterically over a CEV I had of a dragon exploding from the ground out of the middle of a village and eating everyone who lived there after crushing their homes. You could say it shredded my ability to sympathize with anyone. I'd vision large explosions of blood and crushed up body parts. It sure wasn't drug induced apathy since it was accompanied by what I could only describe as mania, but that drugs effects rendered me into a state of insensitivity.

As for DOC and DOM they're just great. DOC is more fun for me. DOI I plan on doing at least once more I'm sure but I'm in no rush to fuck with that compound anytime soon.
 
I've done one drug, not sure if it was DOI or DOB, on 5 occasions. Every trip lasted a total of 30 hours. Stimulation very central, little peripheral. Madcap laughs for hours on end.

But long, long periods of being unable to make up my mind if I liked the drug or not. Not negative effects, mind you. Just a very, very hard time deciding if the effects were definable as pleasurable, and that issue being of great importance and very frustrating to me.

I ended every trip saying something along the lines of, 'well, I guess I give this drug a good review after all', for some reason I could never quite figure out. That was before the mildly twacked-out 2 day comedown hit me, mind you. But every time, I felt positive about someday using it again. I've noticed no ill effects, but then again I've only used it 5 times.

For a rave or festival, I'll take DOx over LSD any day, even though the latter can be a blast, don't get me wrong. DOx is GUARANTEED energy and a good time, which is more than I can ever say for MDMA.
 
had a fucked up experience on doi last weekend. smoked weed and ate my doi at the same time. had mad giggles with the weed, but as the doi kicked in 3hrs later. I was lost. I did not know who I was, I knew who all my friends was. But I just couldn't figure out who I was. Then I started a OCD behavior, i couldn't stop my self from walking in and out of my mates house. in the front door out the back door, in the back door, out the front door, over and over again for like 3hrs. I knew i was in a fucked up loop but I could not stop my self from looping.
I continued to stay confused for the next 10hrs or so. Then I was back, and started to enjoy the rest of my DOI trip :)
 
U R THE GUINEA PIGS

And so far the stuff seems to be safe And so far the stuff seems to be safe And so far the stuff seems to be safe And so far the stuff seems to be safe And so far the stuff seems to be safe And so far the stuff seems to be safe And so far the stuff seems to be safe And so far the stuff seems to be safe
 
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