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Opioids dosing question

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butters!

Greenlighter
Joined
Mar 22, 2012
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hello, i have been taking 120mg of oxy timerealease but ran out. i had some 100mg morphine sulphate pils left over but they dont do much orally. anny way of crushing them up to avoid the time release? i can maybe take half for time release and the other crushed for immediate? best to snort the crushed or swalllow? other than the 120 mg of oxy a day i take 6 to 8 roxy 15mg a day as well,help please
 
Morphine has a very poor oral bioavailability of ~30%, and an even lower intranasal bioavailability of 10%. The best way to administer morphine is rectally, with a bioavailability of 30-60%.

Crush it, put the contents in an oral syringe, add (warm) water, shake rigorously, lay on your side or stomach, stick the syringe in your anal verge and all the way through your anal canal, push the plunger, stay on your stomach for 5-10 minutes to make sure your colon absorbs everything, if you get up and feel seepage, pinch your cheeks together and lie back down.
 
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