Helios.
Ex-Bluelighter
No, you can drop them at the same time if you like.
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MDMA &
Empathogenic
Drugs
Welcome Guest! -
Does Wellbutrin affect MDMA?
- Thread starter wastedwalrus
- Start date
You guys are some of the fortunate ones to be able to roll just as hard while on Wellbutrin; I did it myself some days ago and felt about 30% of the effects.
The question still stands: if I don't take my Wellbutrin for 5-7 days, will I be able to roll as hard as I would normally?
The question still stands: if I don't take my Wellbutrin for 5-7 days, will I be able to roll as hard as I would normally?
ChemicalSmiles
Ex-Bluelighter
BUMP I need to know the exact amount of time it takes wellbutrin to leave your system to roll 100%...... I'll wait the high end of suggestions seeing as I havent rolled in 4 years and am not depressed anymore and just tapered completely off of wellbutrin.
Bushdoctah
Bluelighter
Bad Bad Idea
Why would you be taking E if you are on anti-depressents????? You are asking for #1 very bad drug interactions and #2 a very fucked up psyche!!!! If you are having problems with depression you should absolutly not take E, the comedown could be very very tought for you to bear and very very uncomfortable. If you are taking welbutrin for ADHD I recomend you don't take it at all. I was on that crap for two years and Im willing to bet it will cause you further psychological problems. They don't even realy know how exactly welbutrin works, it does change your brain chemistry however by interacting with dopamine inhibitors. Its a terrible idea to mix E with psychological drugs I can't stress this enough. Ive seen two people go into siezures from that kind of combination. NO FUN PLEASE BE CAREFUL -Love your friend and brother -Ben
Why would you be taking E if you are on anti-depressents????? You are asking for #1 very bad drug interactions and #2 a very fucked up psyche!!!! If you are having problems with depression you should absolutly not take E, the comedown could be very very tought for you to bear and very very uncomfortable. If you are taking welbutrin for ADHD I recomend you don't take it at all. I was on that crap for two years and Im willing to bet it will cause you further psychological problems. They don't even realy know how exactly welbutrin works, it does change your brain chemistry however by interacting with dopamine inhibitors. Its a terrible idea to mix E with psychological drugs I can't stress this enough. Ive seen two people go into siezures from that kind of combination. NO FUN PLEASE BE CAREFUL -Love your friend and brother -Ben
MazDan
Bluelight Crew
Bushdoctah said:
With respect, I think the doctor probably has a better idea of what particular drug a person needs taking into consideration all of the available info.
Chemical smile.............Im not exactly certain myself, and interestingly I have just completed a course of that as well. I am fairly certain I did find some info in the Directory...........maybe try Wellbutrin and MDMA or Zyban and mdma or even try the anti dperessant and mdma threads.
The other thing you could try would be doing a search for the half life of wellbutrin, remebering that you were on it for a while and that means you have a fair bit in your body to get rid of.
I know I have now been off it for a week but I can still tell Im not 100% back to normal yet.
ChemicalSmiles
Ex-Bluelighter
Bushdoctah said:
Ok, obviously you didn't read my post thoroughly. I am off of wellbutrin now with my doctors approval, because I dont need it anymore. I had situational depression which wellbutrin helped to an extent. However, I don't feel I need it at all anymore. I tapered from 300 mgs to 200 in 2 weeks, 200 to 100 in 2 more weeks and from 50 - 0 mgs in 1 week. IO have experienced no withdrawl and I am happy as a lark. Making new friends, and enjoying my first year of college. I know everything you are trying to convey already....... but im a different case than most. I didnt stop taking welbutrin so I could start taking ecstasy again!
AND btw: wellbutrin for ADHD? Never heard of that and personally..... adhd is over diagnosed and I feel that only 5-10 % of the people actually need to be on it. Depression meds are pushed to much by doctors as well, its a cycle. 1 very big money making cycle......... %) Thanks for trying to help though, BL is all about kindness, and harm reduction.
Hmm, not sure how I missed this thread but I don't find any of my posts in it.
I've been taking Wellbutrin daily for 3 years. I've been using E for about 2.5 years. I've never found any kind of adverse reaction between the two, at any dosage or timing.
In general I find if I don't take my normal antidepressant, the effects of the roll are slightly LESS than if I do. Perhaps that's just my unique chemistry, no way to tell. I do seem to use a significantly higher dosage than most people to achieve the same result (I use 3:2 vs my husband who weighs 50% more than me), but I do get to the same result eventually.
As for half-life, I find I tend to run down if I stop taking my antidepressants after about 4-5 days. The listed half-life is 20 hours, so that probably matches up about right considering I do 150mg 2x/day.
However, I don't recommend trying to go 2-3 days without it and then take E. Most likely the withdrawal symptoms will be more of a problem than the normal inhibitor effect if there is any. Just try a higher dosage, and you should be fine. If you're really struggling, I highly recommend supplementing with a B-100 complex in advance (I take one every morning), and maybe some 5-HTP a day or so before.
I've been taking Wellbutrin daily for 3 years. I've been using E for about 2.5 years. I've never found any kind of adverse reaction between the two, at any dosage or timing.
In general I find if I don't take my normal antidepressant, the effects of the roll are slightly LESS than if I do. Perhaps that's just my unique chemistry, no way to tell. I do seem to use a significantly higher dosage than most people to achieve the same result (I use 3:2 vs my husband who weighs 50% more than me), but I do get to the same result eventually.
As for half-life, I find I tend to run down if I stop taking my antidepressants after about 4-5 days. The listed half-life is 20 hours, so that probably matches up about right considering I do 150mg 2x/day.
However, I don't recommend trying to go 2-3 days without it and then take E. Most likely the withdrawal symptoms will be more of a problem than the normal inhibitor effect if there is any. Just try a higher dosage, and you should be fine. If you're really struggling, I highly recommend supplementing with a B-100 complex in advance (I take one every morning), and maybe some 5-HTP a day or so before.
MazDan
Bluelight Crew
Gldm said:
Great post gldm.
Just a reminder for people that the above stuff is specific for Wellbutrin ONLY and is NOT typical of all anti depressants.
Each one is different and you should check out the Directory for info about your specific one.
For example I am on an MAOA and that can be extremely dangerous when taken in conjunction with mdma.
If your not sure, check the Directory or at worst, ask us.
drancer
Bluelighter
I am about to be prescribed Zyban for depression, and that's just fine with me because I want to continue to enjoy MDMA and not have the medication interfere with that - at least, Zyban is a far better choice than SSRI's from what I have read.
However, are there any other drugs in the same category as Zyban/Wellbutrin, or is it pretty much a class of it's own? I can't find anything online that suggest there is another AD that is similar to that. I am asking because Zyban is not on the Australian prescription schedule, meaning that it would be a very expensive course of medication to take.
BTW, I have tried Lovan, Lexapro and Effexor. They all make me feel like shit!
However, are there any other drugs in the same category as Zyban/Wellbutrin, or is it pretty much a class of it's own? I can't find anything online that suggest there is another AD that is similar to that. I am asking because Zyban is not on the Australian prescription schedule, meaning that it would be a very expensive course of medication to take.
BTW, I have tried Lovan, Lexapro and Effexor. They all make me feel like shit!
MazDan
Bluelight Crew
drancer said:
Zyban, also known as Wellbutrin in the USA is not prscribed for depression in Australia...........and I believe its because there have been some bad side effects that mean it doesnt make the safe for use schedules in Australia at ther doses necessary to help depression.
It is however used as an anti smoking aid here in Australia. I recently finished a course and found it was peretty much useless as an anti smoking drug and also useless as an anti depressant..........but that was me...............everyone is different and you should listen to your doctor cos he knows you best.
Regards use with mdma...........my understanding was that it may or may not have an affect..........I never tested it.
Effexor I also tried and didnt mind after the first 3 weeks or so the sitty feelings go away but if your a guy it causes other probs.
Biggest prob for me with Zyban was the not being able to sleep prob...........it drove me nutsier than I already was.
drancer
Bluelighter
Well, Well.. I just got prescribed Well.. I mean Zyban by my pschotherapist after an intense discussion. It's not a routine prescription, I pay the full cost of it. She wants me to try Lovan, I vehemently disagreed!!
My question is, has anyone tried taking half a capsule of this Zyban SR 150mg at a time? I only need 75mg dose, but was worried that the SR meant that I can't break it up or I might break the sustained release barrier that's on the capsule.
150mg in a capsule taken twice a day.. that sounds like an awfully high dose for me! (I am sensitive to medication... and drugs
)
My question is, has anyone tried taking half a capsule of this Zyban SR 150mg at a time? I only need 75mg dose, but was worried that the SR meant that I can't break it up or I might break the sustained release barrier that's on the capsule.
150mg in a capsule taken twice a day.. that sounds like an awfully high dose for me! (I am sensitive to medication... and drugs
)drancer said:Well, Well.. I just got prescribed Well.. I mean Zyban by my pschotherapist after an intense discussion. It's not a routine prescription, I pay the full cost of it. She wants me to try Lovan, I vehemently disagreed!!
My question is, has anyone tried taking half a capsule of this Zyban SR 150mg at a time? I only need 75mg dose, but was worried that the SR meant that I can't break it up or I might break the sustained release barrier that's on the capsule.
150mg in a capsule taken twice a day.. that sounds like an awfully high dose for me! (I am sensitive to medication... and drugs
I haven't tried breaking mine up, they're pretty solid pills. They also don't seem to always completely dissolve on the way through, but the documentation that comes in the box says that's normal.
I'd be wary of cutting them without checking with a pharmacist first. How does your doctor expect you to take 75mg if you're prescribed 150s? That doesn't sound right. Are you sure you got the prescription filled correctly?
You could try getting 150mg XRs which release even slower than the SR tablets and then taking one a day, but I found that produced too much of a high/low for me.
MazDan
Bluelight Crew
You sure they dont mean a single 150mg tablet taken twice a day.........ie 300mg a day in total?
75mgs is a very low ammount.
And why would you argue with your doctor????
75mgs is a very low ammount.
And why would you argue with your doctor????
drancer
Bluelighter
I am just a bit worried about the side effects, that's all. The dose I have been given is 150mg twice a day, but for the first few days just take 150mg once a day. I was just thinking hypothetically that I should break it up and have 75mg twice a day to make it more consistent...![:\](https://bluelight.org/xf/BL_Images/Orig_Emoji/wrygrin.gif "wry grin :\")
I was arguing with my doctor (in a pleasant, non violent way of course) because I was prescribed Lovan a while back and it gave me the freakiest nausea ever, not to mention my reduced response to MDMA, which annoyed me to no end!
I was arguing with my doctor (in a pleasant, non violent way of course) because I was prescribed Lovan a while back and it gave me the freakiest nausea ever, not to mention my reduced response to MDMA, which annoyed me to no end!
drancer said:I am just a bit worried about the side effects, that's all. The dose I have been given is 150mg twice a day, but for the first few days just take 150mg once a day. I was just thinking hypothetically that I should break it up and have 75mg twice a day to make it more consistent...
I was arguing with my doctor (in a pleasant, non violent way of course) because I was prescribed Lovan a while back and it gave me the freakiest nausea ever, not to mention my reduced response to MDMA, which annoyed me to no end!
Nausea isn't really that common from what I've heard from other Wellbutrin users. I've never had it and I tend to get nauseous from a lot of meds. For best effects I suggest you take your 150mg dose at the middle of your day, around lunch. When you transition to 2x/day, shift to morning/dinner. You don't need to eat before taking it, I just find it helps me to remember to take it on time if I associate it with meals. I've never had it cause issues on an empty stomach vs a full one.
150mg is not a very strong dose at all and most people are on the 300mg or even 450mg plans. 150 is a pretty safe level for testing for reaction to it. Too high a dose will usually manifest as increased anxiety and restlesness, which is why it's not commonly prescribed for those who need anti-anxiety meds.
How long are you supposed to be on 150mg 1x/day though? It should be more than a few days, as Wellbutrin has a long initial ramp-up time for a new user. I was on my trial dosage about 3 weeks before I moved to full dosage, and it didn't start producing useful effects until about 3-4 weeks after that.
drancer
Bluelighter
^^ I was on 150mg per day for 5 days and then I moved onto 2 x 150mg each day. I am dosing it similar to what you say - once in the morning and once later in the afternoon (at least 8 hrs apart).
So far, I have tried E on two occasions and I haven't noticed anything different. Similar with acid, nangs, weed (although I hate it with lots of baccy in a joint as I find it tasting more and more worse), DXM, speed and coke. I am glad that none of the effects have been muted so far.
That said, I am surprised to read that the initial ramp up is 3-4 weeks before I get the full effects? I suppose that is true, cos this is my third week and I can feel kind of something, but not overly happy or anything like that. There was a time when I even doubted that it was working at all!
Mind you, I would hate to go back to SSRI's again. I do not like the severe loss of sex drive from those.. or passion for that matter. I go so far as to say they make me feel very unmanly
So far, I have tried E on two occasions and I haven't noticed anything different. Similar with acid, nangs, weed (although I hate it with lots of baccy in a joint as I find it tasting more and more worse), DXM, speed and coke. I am glad that none of the effects have been muted so far.
That said, I am surprised to read that the initial ramp up is 3-4 weeks before I get the full effects? I suppose that is true, cos this is my third week and I can feel kind of something, but not overly happy or anything like that. There was a time when I even doubted that it was working at all!
Mind you, I would hate to go back to SSRI's again. I do not like the severe loss of sex drive from those.. or passion for that matter. I go so far as to say they make me feel very unmanly
drancer said:^^ I was on 150mg per day for 5 days and then I moved onto 2 x 150mg each day. I am dosing it similar to what you say - once in the morning and once later in the afternoon (at least 8 hrs apart).
So far, I have tried E on two occasions and I haven't noticed anything different. Similar with acid, nangs, weed (although I hate it with lots of baccy in a joint as I find it tasting more and more worse), DXM, speed and coke. I am glad that none of the effects have been muted so far.
That said, I am surprised to read that the initial ramp up is 3-4 weeks before I get the full effects? I suppose that is true, cos this is my third week and I can feel kind of something, but not overly happy or anything like that. There was a time when I even doubted that it was working at all!
Mind you, I would hate to go back to SSRI's again. I do not like the severe loss of sex drive from those.. or passion for that matter. I go so far as to say they make me feel very unmanly
5 days is pretty short, but if it's not bothering you at 150x2 then stick with that. The reaction to tobacco is normal, hence why they give people Zyban for quitting.
It took me 3-4 weeks at the start and most people I know say it's roughly similar for them. I can't say if it's the same for an off/on user since I haven't known one. You won't really notice anything major. It'll just be easier to get up and do things instead of moping around. You probably won't notice the difference unless you quit cold for a few days, but I don't recommend that.
Some people say that due to the dopamine reaction it may inhibit the effectiveness of cocaine, but since I never had cocaine before I started using the wellbutrin I can't confirm that. I can say it doesn't really do much for me though, so maybe that's true.