Yes it does.
Methadone is a full agonist opiod, and will raise tolerance just as any other opioid/opiate will.
This sums it up perfectly. It should go without saying that taking opioids of any kind, just like most other drugs, it's all just a matter of becoming dependent, and everyone I know reacts differently to each opioid.
I don't know any of my friends who report having the same experiences/sensation even when we've all taken the same dose and drug. It is however, the general, albeit loose, consensus around here is that most report hydrocodone being noddy and more sedating and some report that it is extremely euphoric, but this is mostly reported by users who do not have much of a tolerance for pain killers.
Between hydrocodone and oxycodone potency wise, lies morphine. Via the oral ROA, it's for the most part widely underestimated. Everyone thinks that bioavailability is the most important thing, hence why so many people rush to shoot it (and shoot it for it's famous rush) unfortunately, most of the morphine that people are injecting illegally comes from pharmaceutical tablets, unfortunately further, most people are using the extended release formulation as opposed to the good pharmaceutical grade IV morphine for injection, or at least the MS IR instant release tablets that can be micron filtered or better yet, prepared for rectal administration negating the use of needles.
Oxycodone is well-known for it's ability to induce a lot of euphoria, and most regular oxyC users report dose-dependent stimulation, which from personal experience I can attest to, it's an odd phenomenon, as most pain killers are generally thought and accepted as CNS depresants (Oxycodone is a
highly potent CNS depressant,
let there be NO confusion whatsoever that oxycodone is a CNS depressant and in combination with other CNS depressants it CAN and WILL not even think twice [as it is incapable of sentient thoughts] or hesitate to end your life, slowly, in stop your breathing, stop your heart, leaving a wake of pain and suffering for everyone in the life you took for granted.
Methadone is no different, in fact, methadone is at least 2-4x stronger than Oxycodone, I've seen adults drop and turn blue and stop breathing after ingesting 20mg of methadone (2 x 10mg [M]-Eslon Tablets) and no other CNS depressants were involved to my knowledge. If she had gone just a few more minutes without immediate medical attention, she would have died for sure. Do not underestimate the power of methadone.
Methadone has some quirks.... 1) How effective it is is hugely dependent on unique body chemistry, and especially for people who don't take methadone often (this is called Acute Dosing), 2) the amount of methadone in your bloodstream is not at all consistent, taken orally there are still rather significant peaks and valleys, ups and downs in plasma levels... this usually stabilizes after you've been taking it for a while consistently (Chronic Dosing). 3) Methadone, or MMT, usually focuses on bringing you up to a blocking dose (70-90mg) so that you can't enjoy your drug of choice, usually heroin, anymore. They basically raise your tolerance so high to opiates that you don't experience any euphoria, and thus in doing so, it's supposed to make it pointless, not to mention extremely expensive and dangerous, to try and break through your blocking dose.
I want to take a second to focus on the danger aspect, since this is an HR community. I'll keep it short and simple. 1) If you mix it with CNS depressants like alprazolam (Xanax) and/or alcohol, or if you try to break through your methadone by doing a huge shot of dope,
you are likely to overdose and die. Methadone is one of the most unforgiving, ruthless, powerful medications I've EVER come across. I've lost too many friends to this fucking drug.
2)
Friends don't let friends mix their methadone with Klonopin/Xanax/Alcohol/CNS depressants. The funerals, just ONE, would make you reconsider the path you're skipping down. Please tread lightly and with care, and be aware that methadone lengthens your QT interval, meaning it messes with the electrical pulses that control your heart beating. It can potentially cause fatal, long QT syndrome, especially when mixed with other drugs that lengthen your QT interval, for example Ondansetron (Zofran).
Unlike Buprenorphine, with methadone, you don't have to worry about precipitating withdrawals, but unlike buprenorphine (when taken by itself), there is no ceiling limit with methadone, meaning the sky is the limit, meaning the more you take, the more side effects you'll get including severe nodding and slowed breathing, and you can die by overdosing on methadone alone, and you would be surprised what it's capable of.
I think that about sums it up, I'm closing this thread because this topic has been covered a million times and is probably better suited for basic drug discussion anyways.
Thanks for the replys I'm an idiot though I should've mentioned my mdone dose is 30mg.
I feel so sick it it feels like a letigitimate flu sick and not WD sick (I've been using for 5+ years so I know how dope sick feels like) I'm wondering if this is because my last dose of mdone was Saturday , I skipped my Sunday dose and I just got soo sick outta nowhere last night . I'm about to bang and take mdone from yesterday (30) + (30) from clinic
hopefully I b high all day
Damn man, looks like you're still hell bent on trying to get bent. Good luck with your recovery.... you're really going to need it. But first..... You're going to have to actually want to get better, which means one day, you'll have to make some MAJOR lifestyle changes and it will be 100000x more difficult then than it would be now if you were to commit to MMT and your program and trying to get sober. Good luck and God Bless.
![:\](https://bluelight.org/xf/BL_Images/Orig_Emoji/wrygrin.gif "wry grin :\")
but anyway...
