Does Ketamine work Orally?

[evo4ever]

Hey all.

I've had crystal ketamine in my possession for months and I occasionally have a line or two but I absolutely hate the detergenty taste of it, the only good thing about snorting it is it never blocks ur nose. Can I take it orally with the same effect of snorting it? Maybe put some of it inside a capsule?

Cheers guys.

 

[KS78]

Bioavailability of Ketamine according to various ROAs:

Intravenous: 100%
Intramuscular: 93%
Intranasal: 25-50%
Sublingual (under the tongue): 30%
Orally (by mouth): 16-24%

 

[falsifiedhypothesi]

Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy - PubMed

Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-methyl-D-aspartate receptor. It has no affinity for gamma-aminobutyric acid receptors in the central nervous system. Ketamine shows a chiral structure consisting of two optical isomers. It undergoes...

www.ncbi.nlm.nih.gov

If you could find a way to inhibit cyp2b6 and cytochrome P450 then you might get decent effects. But that would likely involve mixing at least 1-2 more drugs with it, which doesn't sound safe on the face of it.

By the bioavailability listed above you are probably best off trying sublingual before anything else.

 

[evo4ever]

Well theres only one way to find out, i guess ill put some into a capsule maybe twice the amount I'd snort to make up for the reduced BA. Sublingual is out of the question as it goes into ur mouth which I dont like.

 

[jhjhsdi]

It's very bad for your insides

 

[evo4ever]

It's very bad for your insides

Yeah I'm aware of that but I'm sure it's only bad for ur insides if ur taking it chronically.

 

[axe battler]

I think it has a good rectal BA if you're not one of these people who think it makes them gay, or doing it at a party with lots of people around!