Lysergamides Does Ketamine cause cross tolerance with psychedelics?

[Viraldrome]

I'm having a hard time finding info. I did a bit of K the other day and want to trip next week, usually I wait 2-4 weeks between trips, not sure if K effects tolerance to classic psychedelics?
Also any risk to using K during LSD/mescaline/2-cb trips? I don't see any mention in the dangerous combos thread, but I just want to make sure, Google just returns results for drug treatment places, which are the worst source for accurate information

 

[Pissed_and_messed]

no tolerance, no danger.

 

[Skorpio]

K exerts its psychedelic effects via NMDA antagonism, where psychedelics work via activating specific pathways downstream of serotonin 2a receptors.

The mechanisms of these drugs, and generally the brain areas which produce their effects are quite different. There should be no cross tolerance.

 

[Deleted member 521610]

As said no cross tolerance.

K is safe to use with psychedelics.

K & psychedelics very powerful, the ketamine will remove anxiety and numb you to any fear, and you will go places in your mind that will blow you away.

K & acid combo made in heaven. take lines as needed and sit down on a comfortable couch or bed propped up wit some pillows. set & setting like always. go with the flow, stay grounded in your own being. I no longer trip or anything, but when i did it in 2021, holy shit it changed me as a person 6 tabs + gram of K. The k will extend your trip till you manage to sleep