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Misc Do quinazolines compete with benzos for gaba receptors -making benzos less effective?

THE_REAL_OBLIVION

Bluelight Crew
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Apr 17, 2005
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I'm on xanax or valium daily (have a valium script and xanax script I can renew every 2 weeks, which stops when the other starts) which is really annoying as i'd like to have both at the same time but I hardly can get to the xanax script with more than a couple valiums left.

I've obtained etaqualone to help out, so that I take less benzos. The first time I ordered some was 4-5 months ago when I was still on methadone and it would knock me out cold.

Now that I am on suboxone...I don't know if it's because the product isn't as potent, but 300-400mg barely does anything and when I wake up from bed I always have a headache similar to what alcohol would do when on gone on a night drinking ridiculously like when i was a bit younger (hitting 30 y/o is quite a slap in the face). All these opis and benzos have beaten me down too, I could easily drop 2-3 tabs of good lsd 3 years ago, even snort some pcp and smoke freebase then and it would be a blast. Doing such these days would scare me. Fucking anxiety disorder caused by benzo "tolerance withdrawal". What's funny is that I was on benzos then, 3mg clonazepam a day and I would never get into such feelings, I asked to be benzo tapered cos I was sick of having no feelings and not being able to give a shit which caused me a lot of trouble.

Anyway, sorry for the lyrical digression, I tend to do these :\ Does anyone here feel ludes, etaq, mebroq and any compounds of this class does not synergize with benzos but instead competes with it? Can anybody find any info on how Mandrax (ludes) worked ? I know back then neuropharmacology wasn't very advanced and they barely knew why Methaqualone was a sedative. Does it outcompete benzos ? If so, how could it if benzos stick to a particular subcomplex of the GABA receptors (bz1, bz2 etc.) while I imagine that these should act like alcohol and barbs, indiscriminately affecting GABA at either GABA-A and GABA-B sites ?
Please enlighten me, I've done a lot of snooping around before posting this, to no avail.
 
I have a script of 30 valiums which my psych decided I pick every 2 weeks cos I had a bit of difficulty with compliance (would go weeks without valium and it would be hell). He also scripted me 0,5mg xanax (15) of them every 15 days for panic attacks which made me take more valium causing the vicious circle to happen) When I filled that script I was still having 60 counts of valium a month, it was before the valium was served to me every 15 days. So I go through almost almost all through those 30 10mg valiums in less than 15 days, but thankfully the time to pick up my xanax is 1 week after the week I pick up valium. So it goes like this, pick up 30 valiums, a week later pick 15 0,5 xanax, the week after 30 10mg valiums etc.
 
That seems a little strange, don't you agree? I've never heard of anyone having xanax and valium alternate like that.

My $0.02 would be switch to the 5mg diazepam tablets so you can dose more reliably. The reason I ask is because I also take alprazolam and diazepam however I take them both simultaneously, diazepam to keep the seizures away and alprazolam for severe panic. Have you considered getting stable on diazepam? I highly recommend it!!
 
Insurance allows me to renew the xanax every 15 days since it says take one pill as needed - anxiety/insomnia. In theory it was for every 30 days that the psych wanted me to have them (in a "as needed" plan), thing is they are needed everyday, especially since they are weak 0,5mg. Things will change when I see him again, or just have them upped to 1mg through fax demand by my pharmacy. Government insurance is the one that allows the script to be renewed every 15 days, because it pays for 15 pills, that in theory can be used in 15 days. Nothing weird.

Now, the point of my thread please ? Anyone?
 
Alright, I think I found the secret for this etaqualone freebase. It has to be smoked in much smaller quantities than if eaten. I just euro-vaped (like with freebase cocaine) some in my weed pipe over some cigarette ash. Not only did I get an instant relaxing rush....the stuff tastes exactly like when I would be freebasing my own fishscale cocaine! This cold slightly numbing taste....I am very surprised of the taste, but the effects are now pretty pronounced. I used 35mg and it seems online literature (here and erowid) read up to 100mg safety wise. I'm not sure I'll have another hit, I think I'm going to lie down now :)

Although discussion relating to my original questions are still very welcome.

P.S. Does anyone else get extreme hunger after the rush has subsided ? It's crazy, I never felt this hungry since before I got on methadone which allowed me to save money for food. But even then now after 4 raspeberry jam toasts I feel my stomach grrrr and it's kinda painful even, like when you are starving after a long shift at work and didn't eat the whole day.

btw tricomb : I am stabilized on valium, the reason I am on valium is from when I self-initiated taper from the 3mg of clonazepam I was on a day then, I felt sick of feeling like a zombie unable to have intense feelings about anything. We did it Ashton style but I couldn't go lower than 20mg, because he didn't want to go as slow when I was at 20mg, going about : "Come on, you only got 20mg left !", an ER doctor saved my ass after we had a serious discussion about it, he put me back on 2 x 10mg valium a day and it's been going on since late 2010 now.
 
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