bupemonkey
Bluelighter
- Joined
- Jul 13, 2008
- Messages
- 70
Buprenorphine's sublingual absorption is around 30% into the veins under your tongue. Intranasal is 40-50%. So, you definitely get more into your bloodstream (& brain) if you snort you subs. It hits faster too. And no, naloxone will not kick bupe off the receptors. That is, if you are already on bupe, nalaxone will not displace it due to much lesser receptor affinity.
Naltrexone, however, from what I read will start displacing bupe off the receptors.
Naltrexone, however, from what I read will start displacing bupe off the receptors.