Do dopamine releasing drugs not work if you've taken a re-uptake inhibitor earlier?

[lynx2051]

Say if I took MXE now, then four hours later took a releasing agent drug like 6-apb, would the 6-apb not work properly?

 

[nAON]

The opposite, you might get problems with excess dopamine such as psychosis. I'd leave the APB for another day.

 

[benzofan]

I confirm it is exactly the opposite (and dangerous) way

 

[lynx2051]

Thanks. It's just that I've heard that people who take cocaine, then later on take releasing agents like MDMA later stop MDMA from working.

 

[Doug2113]

that's because cocaine releases dopamine and depletes your receptors of it...re-uptake involves the amount of time left in the synapse (and thus affecting you).