Opioids Do different ROA's of opioids affect different..

[Wesley_pipes_27]

How do different ROA's of opioids effect different peak plasma concentrations in blood, urine, etc.?
For instance, obviously IV injection would cause greater concentrations of the drug in the blood over the short term, however how does this ROA effect concentrations in urine, hair follicles, etc? If a person were to take an opioid/opiate orally versus intravenously how does that affect testable concentrations in blood, urine, etc. Lesser? Greater? Etc.

WP


NOTE: I am writing a paper for my Sociology class on "The Impact of Illicit Drugs & Drug Testing in the Workplace in Modern Society." This information is for research purposes for my paper.

Mods, I hope this question is okay under the BLUA as it's not about how to beat drug tests or how long you can test for a specific substance etc.

 

[Znegative]

I imagine it wouldn't make much of a difference unless the oral medication is a time release formula. It also would have to do with how often the person uses this substance, and how much they are using. For instance if someone has been using heroin intravenously for a month, I imagine that it would stay in the system longer an some one who injected heroin once a month, due to the slight buildup that happens with repetitive drug use. But I've heard that drugs also show up I'm hair follicles for a real long time and I doubt it would make a difference how you used the substance. In general the ROA will not affect the half life, just the duration

 

[Albion]

Even if you are asking for academic purposes, this is at its core a drug testing question, which we unfortunately don't allow. Closed.