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Do 2c-* drugs put strain on the heart/cardiovascular system? (+question)

bignbrown

bignbrown

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Ive done them plenty of times before but not for over a year.

I have some 2ci and 2ce coming and im wary these days about putting my heart under alot of strain, i remember 2ci being quite stimmy but i never got it that bad like some people report, just lovely visuals.

Also i really dont want an intense trip, what dose of each would you suggest, i know snorting 2c''s hurts, but im thinking with 2ci just snort little 5mg bumps (waiting a good 15 minutes before each one) until i get where i want to be?

2ce is just awful snorted, but im not sure on a dose, im thinking 15mg might be quite manageable. (oral)

I will have a few xanax and temazes if i get a bit anxious. Note im not taking these for any introspective trips or anything like that, purely for fun. I know 2ce can be quite dark but i think mixed with a few temazepams or maybe phenibut would be nice and chilled and reduce bodyload, i honestly dont find gaba drugs to dull the trip as im only in it for the visuals and giggles, nothing else :)

Any tips on dosages, reducing bodyload and ROA would be appreciated :) I also have the option of plugging, but im not sure on dosages, ideally i want a mild trip, thanks.

Thanks
 
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2c-* are cardiovascular stimulants, yes. They bind to adrenergic receptors (what norepinephrine and adrenaline bind to).

Keep your doses under 15mg for "lighter" trips. Even 10mg of 2c-E can be a lot.

Plugging and insufflation will roughly double the potency of the drug.
 
thank you, are they strong cardio stimulants (like say coke, amp, mephedrone etc) or more mild?

Will keep to low doses!
 
They are similar to ephedrine in cardiac stimulant effects, I would say. Certainly not a problem except in overdose, but not an insignificant factor either.
 
it looks like a djin =D

About the 2C´s, theres some 2C´s that seem to be less stimulating than 2CE and 2CI.

2CD and 2CC are the two first that springs to mind. maybe check them out, if you worry alot about cardiovascular strain.

Or maybe go for some tryptamines.....I can recommend 4-ho-met for a strong visual experience, not that far from what you could expect from a 2C.
 
I find any dose higher than 15mg of 2C-E will make my pinky fingers tingle. Don't know if that bit of info is worth anything to the argument but I figure I'd drop 'er in here anyhow.
 
This study from PLoS ONE. Drugs tested were 2c-E, 2c-B, 2c-T-2.

All of them have affinity at alpha-2 adrenergic receptors. 2c-B and 2c-T-2 hit the beta adrenergic receptors too.
 
I did 2c-e two days in a row a few days ago. I can definitely agree with the stimulating properties but at the same time, the body load kept me from moving too much. I moved around but had the tendency to sit down. Both times I took 25mg. I had an excellent trip both times but the first time I dosed later in the evening and ended up falling asleep before the end of the trip which happens to me if I'm tired/dose late (for my schedule anyways, maybe not late for all.)
 
Fagott said:
it looks like a djin =D

About the 2C´s, theres some 2C´s that seem to be less stimulating than 2CE and 2CI.

2CD and 2CC are the two first that springs to mind. maybe check them out, if you worry alot about cardiovascular strain.

Or maybe go for some tryptamines.....I can recommend 4-ho-met for a strong visual experience, not that far from what you could expect from a 2C.
Click to expand...

4-ho-met is superb, very shroom-like, easy to "top-up" with, minimal nausea. Highly recomended :)

For a mild 2c-e dose, I wouldnt go higher than 12mg, & to reduce nausea & stomach disconfort I'd halve the dose & swallow an hour apart. An 8mg dose would probably be sufficient if your tolerance is down & you're not looking for a heavy trip.
 
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