DL-Phenylalanine VS. L-Tyrosine for Depression (Anhedonia)

[punkftl]

i am currently taking Wellbutrin Sr. 300mg, Dexedrine immediate release 30mg., for my depression with Anhedonia.
i am also taking 100mg methadone for opiate dependency and 2mg xanax to help me sleep.
i have been taking L-Tyrosine 2,000mg. (500mg X 4 pills) in the afternoon on an empty stomach an hour before my dexedrine.
i just bought a bottle of DL-Phenylalanine and on the bottle it says not to take it with any stimulant..it does not say that on the l-tyrosine bottle.
is it because the D isomer in the Phenylalanine is suppose to convert into PEA, or Phenethylamine, which is also considered stimulating?
i might try taking 2,000mg DL-Phenylalanine in the morning on an empty stomach and continue the L-Tyrosine...
OR...there is a supplement called Mucuna pruriens which contains a high amount of natural l-dopa which is one step away from dopamine compared to l-tyrosine (L-Tyrosine--L-dopa--dopamine--norepinephrine--epinephrine).
any opinions, comments? thanks

 

[Tsukasa]

The D-isomer does not convert to PEA. The L-isomer actually converts to PEA and L-tyrosine. The D-isomer is a synthetic amino acid that just inhibits enkephalinase, thus inhibiting breakdown of enkephalins. DL-phenylalanine is definately a better choice than tyrosine IMO.

Taking tyrosine or phenyl with a stimulant may cause overstimulation in those who are very sensitive to stimulants, but nothing serious.

Mucuna pruriens would be more like a drug really. The dopamine that gets converted from the L-dopa, gets immediately released. It even gives me some strong euphoria at higher doses. Might have done some damage to my DA receptors. You can't do that with the other amino acids that eventually metabolize to DA. Theirs a lot of risks associated with l-dopa supplementation. 1/5 people on L-dopa treatment will develop psychosis. It can also cause dependence (it also contains nicotine btw), and cause withdrawal symptoms similiar to parkinsons disease, and such.

Go with the DL-phen IMHO. It would be the best to replenish your pleasure neurotransmitters and the safest too when it comes to combining with drugs.

 

[bingoliket]

Is it safe to combine Phenylalanine with stimulants like amphetamine/Adderall or methylphenidat/Ritalin? (The purpose is to avoid tolerance.)

I just wanted to make sure, since I read something about not combining aspartame "...and other neurotoxic excitatory substances such as monosodium glutamate (and aspartame)."

# 7 in this thread:

http://www.bluelight.ru/vb/showthread.php?t=97021

 

[bingoliket]

Bump!

Anyone?