• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums
  • BDD Moderators: Keif’ Richards | negrogesic

Diphenhydramine versus Scopolamine effects?

D

drfeelgood1

Bluelighter
Joined
Oct 15, 2005
Messages
632
Quick question here, does diphenhydramine in way resemble the efffects the same way as scopolamine esp. when taking over the recommended dose?
So, I even heard that diphenhyramine in a way is the same as scopolamine. Is this true?
 
They are not exactly the same, but they both have anti-cholinergic effects (dry mouth, urinary retention, blurred vision) and both will make you delirious if you take too much. Diphenhydramine is a sedating antihistamine often used for insomnia, and scopolamine (hyoscine) and is mainly used for motion sickness or to dry up respiratory secretions in terminally ill patients. It also dilates pupils and slows down the gastro-intestinal tract, and used to be used for insomnia. Scopolamine is one of the alkaloids found in Datura.

To answer your question, yes, they would both cause delirium if you take over the recommended dose.. I would not recommend it!
 
I agree with Effie. Diphenhydramine is one of the things that you do once, and vow; NEVER AGAIN.
 
IMO, delirium is something everyone should try once, it's really a mindblowing experience to become schizophrenic for a day and to see how those people live out every day. But not without a sitter and proper precautions.
 
I'm pretty sure there's no real way that you can live looking through the eyes of someone with severe schizophrenia without being schizophrenic. All that diphenhydramine will do to you in extremely large doses is kind of put you in an almost hypnotic state of mind. Kind of like when you're really sleep deprived and you don't have anymore dope to keep you up.
 
Ok as a person who has experienced delerium under the effects of dimenhydrinate aka dramamine aka gravol and unintentional delirium under the influence of scopolamine i would just suggest staying the hell away from either of them unless it is for medical purposes! Run like hell if your thinking of using diphenhydramine, dramamine, scopolamine or any other anti-cholinergic as a recreational drug as they are NOT in anyway recreational. dimenhydrinate was horrible beyond words and i don't know what would top it really. Being injected with narcan while in the midst of a huge fentanyl addiction might be worse but wouldn't last as long :\
 
Doug2113 said:
I'm pretty sure there's no real way that you can live looking through the eyes of someone with severe schizophrenia without being schizophrenic. All that diphenhydramine will do to you in extremely large doses is kind of put you in an almost hypnotic state of mind. Kind of like when you're really sleep deprived and you don't have anymore dope to keep you up.
Click to expand...

Um, no. It causes delirium and hallucinations that are indistinguishable from reality (As opposed to LSD hallucinations which you know are hallucinations)

If you see spiders while delirious, you're going to believe there are really spiders there.
 
JackiesBabyy said:
Um, no. It causes delirium and hallucinations that are indistinguishable from reality (As opposed to LSD hallucinations which you know are hallucinations)

If you see spiders while delirious, you're going to believe there are really spiders there.
Click to expand...

Or you yell at yourself and you can't tell if you said it outloud, if the people staring at you are there, not there completely insane or if your insane. The spider thing is quite common with dramamine ugh jesus i couldn't look at one of those pills for like 5 years after that :p
 
JackiesBabyy said:
Um, no. It causes delirium and hallucinations that are indistinguishable from reality (As opposed to LSD hallucinations which you know are hallucinations)

If you see spiders while delirious, you're going to believe there are really spiders there.
Click to expand...

Hallucinations are part of schizophrenia and part of delirium but they are not the same - delirium is not psychosis. Amphetamine psychosis is the closest you can get to schizophrenia, and can be indistinguishable at first (schizophrenia has a minimum duration of symptoms and a requirement not to be caused by drugs) but you need a dopaminergic drug, not an anticholinergic.

Delirium (and stim psychosis!) is not fun and it is not something everyone should experience IMO, that's not HR advice!
 
Dissociative drugs, especially proper subanesthetic doses thereof, can be a good imitation of schizophrenia too.

Diphenhydramine does resemble scopolamine in many of its effects e.g. anticholinergic activity, opioid potentiation etc. but AFAIK scopolamine is not an antihistamine nor is it a sodium channel blocker.
 
I always presumed that was due to the dopamine reuptake inhibition aspect of drugs like ketamine? Hadn't thought about it in too much detail though I must admit.

I don't think scopolamine is an antihstamine, but I have no idea about a sodium channel blocker so will bow you your superior knowledge Sek :)
 
Last edited:
I've taken a dose of 300mg of DPH before (and I took them to sleep) and I didn't see shit other than things had a very faint fuzzy look to them. And I've never actually hallucinated on anything other than Salvia (which wasn't really a hallucination so much as it was kaleidoscopic patterning), DXM (which was just complete dissociation at 960mg), and methamphetamines.

The first time I did x on dope, I had probably smoked about a 1/4 of a gram and snorted an entire tab (first time snorting the whole one). I don't remember hardly anything of that night. I just remember coming out of it for maybe 15 seconds, see something and then everything was just kind of rushing to the point that I literally wasn't there and couldn't mentally process anything. I'm guessing I smoked more dope after railing that tab, cause I did that around 7 PM and things didn't become clear for me again until 8 AM the next morning. I do remember a couple of conversations where I thought one of my best friends from high school was a cop, and I even asked him if he was one.

That experience included delusions, hallucinations (or as close to ones that I've ever had without complete dissociation), and paranoia, so I'm gonna have to go with effie on the meth psychosis-schizophrenic relation there as it contained two positive symptoms, one negative symptom, and many cognitive symptoms; but I also go with sekio on his claim that dissociatives can cause schizophrenic-like effects. On LSD I never had hallucinations. I had beautiful visual effects, but I never did a ton of it at once (I would like to do half a strip someday though lol). Psilocybin Mushrooms just gave me distortions/tracers.

I don't think delirium necessitates that you completely believe whatever you see. Delusions, however, are blatantly overly false things are believed by the person (i.e. delusions of grandeur-people believing they're god-or how Cartman on South Park thinks he's cool lol). I'm just saying, I've taken quite a decent amount of DPH at one time and I don't see any purpose of taking this drug than to sleep/take for allergies.
 
sekio said:
Dissociative drugs, especially proper subanesthetic doses thereof, can be a good imitation of schizophrenia too.

Diphenhydramine does resemble scopolamine in many of its effects e.g. anticholinergic activity, opioid potentiation etc. but AFAIK scopolamine is not an antihistamine nor is it a sodium channel blocker.
Click to expand...

I knew it wasn't a anti-histamine but i had no idea that diphenhydramine had any effects on the sodium channels. Oh well ya learn something new everyday :)
 
You must log in or register to reply here.
Top