Opioids Dihydrocodeine (DHC) in combination with oral Morphine

[pally pete]

As per the title...

I've taken Morphine orally on countless ocassions, but it's usually a disappointment whatever the dosage (apparently only 30%-40% crosses the BBB). I've also taken Dihydrocodeine (DHC) on countless ocassions, yet with the DHC I've had some more varying results. I realise I have a tolerance (semi-permanent) as I can go for over 6 months with zero Opioids - yet 160 mg Oxy will barely touch me. Anyway, over the years I've had some great times on DHC - Full blown nods, that sense of warmth/contentment, other more pleasant stimulating effects (which I find unique amongst Opioids) antidepressant effects, and then there have also been plenty of letdowns where I just end up itching the whole time...

So does anybody has any advice or experience mixing the 2. Will they poteniate/synergise/ or just cancel each other out

My usual staring dose of Dihydrocodeine (DHC) is 600 mg. And my usual starting dose is of Moprhine Sulphste (Morphgesic SR) is 200 mg

Any help/advise/suggestions all welcome. Thanks

 

[ghostandthedarknes]

As per the title...

I've taken Morphine orally on countless ocassions, but it's usually a disappointment whatever the dosage (apparently only 30%-40% crosses the BBB). I've also taken Dihydrocodeine (DHC) on countless ocassions, yet with the DHC I've had some more varying results. I realise I have a tolerance (semi-permanent) as I can go for over 6 months with zero Opioids - yet 160 mg Oxy will barely touch me. Anyway, over the years I've had some great times on DHC - Full blown nods, that sense of warmth/contentment, other more pleasant stimulating effects (which I find unique amongst Opioids) antidepressant effects, and then there have also been plenty of letdowns where I just end up itching the whole time...

So does anybody has any advice or experience mixing the 2. Will they poteniate/synergise/ or just cancel each other out

My usual staring dose of Dihydrocodeine (DHC) is 600 mg. And my usual starting dose is of Moprhine Sulphste (Morphgesic SR) is 200 mg

Any help/advise/suggestions all welcome. Thanks

if 160mg of oxy barely touches you, i think you're outta luck unless the oxy is the dreaded OP

 

[Las Veghost grower]

I I never understood this “permatolerance” Iv been on retardel large habits of heroin for long periods of time , around a decade , and when I stop for even 2 weeks the first couple times back I’ll get loaded of half a point….in fact Iv never heard anyone speak of permatolerance in my area…I think it must be a fent specific issue….cause around here people talk about how going to jail sucks but getting out is epic cause of the fact you can get high as fuck for cheap as shit again…I’m great full Iv never done fent cause having a permatolerance would suck dick

 

[LivingOnValium]

I'm afraid there's nothing to do to help this than up The dose. With 1 year of complete sobriety i relapsed and needed 60mg to Even catch a nod (not Even a great which would have requires 80mg.

My tolerance alone made My Life as fiemd and i got on The maintenance.

 

[Xorkoth]

I I never understood this “permatolerance” Iv been on retardel large habits of heroin for long periods of time , around a decade , and when I stop for even 2 weeks the first couple times back I’ll get loaded of half a point….in fact Iv never heard anyone speak of permatolerance in my area…I think it must be a fent specific issue….cause around here people talk about how going to jail sucks but getting out is epic cause of the fact you can get high as fuck for cheap as shit again…I’m great full Iv never done fent cause having a permatolerance would suck dick

Really, interesting... I got out of the dope game WAY before fent was around, and never even IVed. But I have an insane permatolerance to opiates. 50mg of hydrocodone won't even do anything if I haven't touched an opioid in years. I quit and was clean for 5 years and had 100mg of morphine my first time back, I got high, for sure, but used to be I could take 20mg of hydrocodone and be high as hell, when I was taking opiates regularly. 100mg of morphine was just decent. It's super annoying.

 

[Las Veghost grower]

Really, interesting... I got out of the dope game WAY before fent was around, and never even IVed. But I have an insane permatolerance to opiates. 50mg of hydrocodone won't even do anything if I haven't touched an opioid in years. I quit and was clean for 5 years and had 100mg of morphine my first time back, I got high, for sure, but used to be I could take 20mg of hydrocodone and be high as hell, when I was taking opiates regularly. 100mg of morphine was just decent. It's super annoying.

Yea it’s kinda weird I just though it was some fent phenomenon, but I guess it must just be individual body chemistry ? Who knows,. Don’t get me wrong my tolerance will skyrocket fast I’ll only get high off a tiny bit maybe 2-3times tops before I’m back to atleast a gram a day, Iv only ivd a handful of times, mostly cause this chick I was with was a Iv user so I did it just out of pressure but still prefer smoking..either way I’m glad I can still get back to a somewhat normal baseline

 

[TheUltimateFixx]

Really, interesting... I got out of the dope game WAY before fent was around, and never even IVed. But I have an insane permatolerance to opiates. 50mg of hydrocodone won't even do anything if I haven't touched an opioid in years. I quit and was clean for 5 years and had 100mg of morphine my first time back, I got high, for sure, but used to be I could take 20mg of hydrocodone and be high as hell, when I was taking opiates regularly. 100mg of morphine was just decent. It's super annoying.

I think there's genetic differences in metabolism. It's the only way I can explain it.

It took me a good two months of continuous daily use to get a habit while I've seen other people get hooked way quicker. And like now I do have to watch the dependence because one thing that seems to be universal is once you HAVE had a habit, your body builds up to that again real quick. On the other hand my tolerance also drops equally quick.
Like after a good five years of full dependence and constant use I can still use weekly and still feel the effect and not get a problem. I know others who have to leave 3 weeks between single usage or they're in trouble. So must be an individual genetic factor at work.