Opioids Difference in large vs. small dose opiates and withdrawal

[drkiv]

Hey guys and girls. First post but long time reader.

Having withdrawn from large doses of oxy, I know how painful it is.

I recently (3 months ago) started a small but regular opana habit. Taking 10mg - 20mg per day.

Would this small amount still affect my brain's chemistry as far as endorphins, dopamine production, etc?

Will my brain "bounce back" quicker? I understand flooding your brain with 100's of mg of oxy a day will cease all production of certain chemicals. Will 15ish mg cause my brain to do the same?

I expect not, but you never know. I've read many surprising things on here to the contrary.

I'm not looking forward to feeling like crap (who is?) but taking the necessary steps. I'm just done with this... And yes, doing support groups and 12 step meetings.

 

[twotoomany]

Opana, or oxymorphone, is significantly stronger than oxycodone. Roughly 2x as strong, oral dose. If you're shooting it or snorting it, that number goes WAY up. According to the opiate converter I used, 20 mg of IV oxymorphone is equivalent to 400mg oral oxycodone. ROA is gonna play a huge role in this discussion.

 

[Opanaking]

Are you snorting or eating them? If your eating them your only getting 1-2mg's of oxymorphone a day in your system. Chances are you'll experience minor withdrawal.

If your snorting them your withdrawal will be significantly worse. I'm sure your not IVing them or your tolerance would have skyrocketed already.

When you take an addictive opiate for 3 months your going to have a withdrawal.

 

[drkiv]

Yes, insulfalation. No iv (thankfully).

I'm now 24 hours in. The only things I have taken are sporadic doses of Advil, 5htp, multi vitamins and kratom. Kratom dosing has been 2 capsules (1-1.5 grams) every 4-6 hours. I've been active, no issues other than lower than normal energy levels and slight aches. I will state that I have been taking 5htp for about 3 weeks now and feel like that has helped my mood. No depression symptoms. We'll see how the next 24 hrs goes.

 

[The Dope Man]

5htp is a joke. your feeling a placebo effect if anything.

As for you opana problem. Youve ben taking a solid dose for 3 months, your ganna have a bad time. Oxymorphone has AWFUL withdraws. MUCH worse than dope or oxy. Because of the long half life of oxyM your also ganna be withdrawing for a while and if your unlucky enough to suffer PAWS those will last longer as well compared to if you were using dope/oxy for those 3 months.

use kratom for the next 3-4 days to help ease the transition than go cold turkey from there.

You should also stock up on some OTC meds. look in the opiate withdraw megathread.

 

[drkiv]

Interesting. I've heard that oxyM had a short half life that made withdrawals much more intense but shorter than other opiates.

Your post has given me a lot to think and research about. Thanks... Well beyond the first 24 hours. No walk in the park, but it's nice not worrying about feeling like crap if I didn't grab a pill because I already do! But not near as bad as I initially had feared. We'll see how the 28-48 hour mark turns out. Just took melatonin, Advil and multi vitamin. I'm curious to see how RLS will be as that has been my biggest issue/concern. Not worried about mental aspects, depression, etc.