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  • BDD Moderators: Keif’ Richards

Dextroamphetamine tolerance and DXM

SerotonergicHaze

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Nov 30, 2011
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Hello, sorry for my UTFSE question, but I have some questions about dexedrine tolerance + dxm

Since around a month ago, I've been prescribed dextroamphetamine, in the reasonably modest dosage of 10mg per day (5mg in the AM and another in the PM). Goes without saying that that dosage didn't cut it for long, so I gradually was upping my dose, to around 15mg in the morning, and 15mg in the afternoon. I've also been taking Magnesium pills for tolerance prevention.

I think I have gained a tolerance, and I want to keep this under control. I'll be abstaining from my amp for a week or so. There has been much discussion on ADD about the use of NMDA antagonists such as DXM or Ketamine to upregulate dopamine receptors and attenuate tolerance

Now, the question is quite simple. During this one week amp abstinence period, how much should I take for tolerance prevention. Would like 30mg DXM a day be enough, since cough medicine starts to get expensive. Or could even less do?

Secondly, how much would be needed to retard tolerance. Considering that there are some questions raised about the long term effects of NMDA antagonists, I would like to keep the dose as low as possible. Would something like 10mg suffice

Would appreciate any feedback :)

Cheers
SH
 
From what I understand, 30-60mg daily is the recommended dose of DXM for tolerance regulation.

Others may / will have more input on this, as I don't have a ton of personal experience with this. A bit, but mostly from reading here and elsewhere online.
 
yes, i have been doing this for a while and i think it works (placebo?). i notice it more with stronger NMDA-antagonists like MXE or ket than with DXM, but when all i had was DXM i would take 75-90mgs daily for 2 weeks straight and notice a difference
 
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